Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCL4,CCL4L1,CCL4L2
  • Mouse genes Ccl4
  • Rat genes Ccl4
  • Zfish genes ccl35.1,ccl35.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031726	CCR1 chemokine receptor binding	CCL4	IPI	UniProtKB:P32246	Human	PMID:7545673
Molecular Function	GO:0031730	CCR5 chemokine receptor binding	CCL4	IPI	UniProtKB:P51681	Human	PMID:10383387
Molecular Function	GO:0031730	CCR5 chemokine receptor binding	CCL4	IPI	UniProtKB:P51681	Human	PMID:10679098
Molecular Function	GO:0008009	chemokine activity	Ccl4	IDA		Rat	PMID:10679105|RGD:68880
Molecular Function	GO:0042802	identical protein binding	CCL4	IPI	UniProtKB:P13236	Human	PMID:20959807
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9BRI3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9BRI3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:P30825	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:P34972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q6IN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q86WB7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9NPL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9NYW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9NZD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4	IPI	UniProtKB:Q9P0N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9BRI3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:P30825	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:P58418	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q12908	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q6IN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q6N075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q7RTX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q8TBB6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9H7M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9NQX7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCL4L1	IPI	UniProtKB:Q9NW97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ccl4	IPI	PR:P51675	Mouse	PMID:7594543
Cellular Component	GO:0005615	extracellular space	Ccl4	IDA		Mouse	PMID:22960654
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Ccl4	IDA		Mouse	PMID:24486487
Biological Process	GO:0006954	inflammatory response	Ccl4	IDA		Rat	PMID:10679105|RGD:68880
Biological Process	GO:0006954	inflammatory response	Ccl4	IEP		Rat	PMID:12144807|RGD:2303104
Biological Process	GO:0030595	leukocyte chemotaxis	Ccl4	IDA		Rat	PMID:10679105|RGD:68880
Biological Process	GO:0043922	negative regulation by host of viral transcription	CCL4	IDA		Human	PMID:10841574
Biological Process	GO:0051928	positive regulation of calcium ion transport	CCL4	IDA		Human	PMID:8699119
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	CCL4	IMP		Human	PMID:10679098
Biological Process	GO:2000503	positive regulation of natural killer cell chemotaxis	CCL4	IDA		Human	PMID:7545673
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Ccl4	IMP		Rat	PMID:10679105|RGD:68880
Biological Process	GO:0043117	positive regulation of vascular permeability	Ccl4	IDA		Rat	PMID:10679105|RGD:68880
Biological Process	GO:0009636	response to toxic substance	CCL4	IDA		Human	PMID:10841574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern