Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ccnb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CCNB1
- Mouse genes Ccnb1
- Rat genes Ccnb1
- Zfish genes ccnb1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	CCNB1	IDA		Human	PMID:24746669
Molecular Function	GO:0060090	molecular adaptor activity	CCNB1	EXP		Human	PMID:12220679
Molecular Function	GO:0005113	patched binding	CCNB1	IPI	UniProtKB:Q13635	Human	PMID:11331587
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q99640	Human	PMID:10373560
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:12612082
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q9NPC3	Human	PMID:12612082
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q96JB5	Human	PMID:15790566
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:O75618-1	Human	PMID:17283331
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:17283331
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:18337751
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:18408765
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q13635	Human	PMID:19502428
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:19879842
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P61086	Human	PMID:20965177
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q0VD86	Human	PMID:21540187
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q96PU4	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q99640	Human	PMID:23397142
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:23543736
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:23799914
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:24358021
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P46527	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q99640	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:27626412
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:Q99640	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:33037310
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P46527	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P46527	Human	PMID:8756624
Molecular Function	GO:0005515	protein binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:9001210
Molecular Function	GO:0005515	protein binding	Ccnb1	IPI	PR:Q9Z255	Mouse	PMID:12525704
Molecular Function	GO:0005515	protein binding	Ccnb1	IPI	PR:Q8VH31	Mouse	PMID:12525704
Molecular Function	GO:0005515	protein binding	Ccnb1	IPI	MGI:MGI:1346325	Mouse	PMID:12124778
Molecular Function	GO:0005515	protein binding	Ccnb1	IPI	PR:P22339	Mouse	PMID:12124778
Molecular Function	GO:0005515	protein binding	Ccnb1	IPI	PR:P48316	Mouse	PMID:12124778
Molecular Function	GO:0019901	protein kinase binding	CCNB1	IPI	UniProtKB:P53350	Human	PMID:12524548
Molecular Function	GO:0019901	protein kinase binding	CCNB1	IPI	UniProtKB:P06493	Human	PMID:24746669
Molecular Function	GO:0019901	protein kinase binding	Ccnb1	IPI	RGD:2319	Rat	PMID:19821535\|RGD:2316313
Molecular Function	GO:0044877	protein-containing complex binding	Ccnb1	IPI	RGD:2319\|UniProtKB:Q01552	Rat	PMID:14512566\|RGD:2316351
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	CCNB1	IPI	UniProtKB:Q7Z6J8	Human	PMID:15749827
Cellular Component	GO:0005813	centrosome	CCNB1	IDA		Human	PMID:12524548
Cellular Component	GO:0097125	cyclin B1-CDK1 complex	CCNB1	IPI		Human	PMID:17495531
Cellular Component	GO:0097125	cyclin B1-CDK1 complex	CCNB1	IDA		Human	PMID:24746669
Cellular Component	GO:0005737	cytoplasm	CCNB1	IDA		Human	PMID:11331587
Cellular Component	GO:0005737	cytoplasm	CCNB1	IDA		Human	PMID:17850284
Cellular Component	GO:0005737	cytoplasm	CCNB1	IDA		Human	PMID:20725088
Cellular Component	GO:0005737	cytoplasm	Ccnb1	IDA		Mouse	PMID:17325031
Cellular Component	GO:0005737	cytoplasm	Ccnb1	IDA		Rat	PMID:19298605\|RGD:2314685
Cellular Component	GO:0005829	cytosol	CCNB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Ccnb1	IDA		Mouse	PMID:9539739
Cellular Component	GO:0005759	mitochondrial matrix	CCNB1	IDA		Human	PMID:24746669
Cellular Component	GO:0005759	mitochondrial matrix	Ccnb1	IDA		Mouse	MGI:MGI:5883204\|PMID:24746669
Cellular Component	GO:0005634	nucleus	CCNB1	IDA		Human	PMID:11331587
Cellular Component	GO:0005634	nucleus	CCNB1	IDA		Human	PMID:16109376
Cellular Component	GO:0005634	nucleus	CCNB1	IDA		Human	PMID:20725088
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Mouse	PMID:19376971
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Mouse	PMID:16489008
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Mouse	PMID:14993286
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Mouse	PMID:17325031
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Rat	PMID:16271231\|RGD:2315993
Cellular Component	GO:0005634	nucleus	Ccnb1	IDA		Rat	PMID:19821535\|RGD:2316313
Cellular Component	GO:0000940	outer kinetochore	CCNB1	IDA		Human	PMID:18195732
Cellular Component	GO:0000922	spindle pole	CCNB1	IDA		Human	PMID:18195732
Biological Process	GO:0071398	cellular response to fatty acid	Ccnb1	IEP		Rat	PMID:14674679\|RGD:2316349
Biological Process	GO:0071456	cellular response to hypoxia	Ccnb1	IEP		Rat	PMID:12374461\|RGD:2316579
Biological Process	GO:0071283	cellular response to iron(III) ion	Ccnb1	IEP		Rat	PMID:18254965\|RGD:2316320
Biological Process	GO:0071407	cellular response to organic cyclic compound	Ccnb1	IEP		Rat	PMID:19298190\|RGD:2316316
Biological Process	GO:0048565	digestive tract development	Ccnb1	IEP		Rat	PMID:17692466\|RGD:2316322
Biological Process	GO:0001701	in utero embryonic development	Ccnb1	IMP	MGI:MGI:2429976	Mouse	PMID:9539739
Biological Process	GO:0000278	mitotic cell cycle	Ccnb1	IEP		Rat	PMID:19821535\|RGD:2316313
Biological Process	GO:0007080	mitotic metaphase plate congression	CCNB1	IMP		Human	PMID:18195732
Biological Process	GO:0007052	mitotic spindle organization	CCNB1	IMP		Human	PMID:18195732
Biological Process	GO:0010629	negative regulation of gene expression	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0001556	oocyte maturation	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0001556	oocyte maturation	ccnb1	IDA		Zfish	PMID:24735541
Biological Process	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	CCNB1	IMP		Human	PMID:18195732
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Ccnb1	IDA		Rat	PMID:15253691\|RGD:2301353
Biological Process	GO:0045787	positive regulation of cell cycle	Ccnb1	IDA		Mouse	PMID:22053081
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Ccnb1	IMP		Mouse	PMID:22053081
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	CCNB1	IDA		Human	PMID:24746669
Biological Process	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport	CCNB1	IDA		Human	PMID:24746669
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	CCNB1	IMP		Human	PMID:18195732
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0045860	positive regulation of protein kinase activity	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0006468	protein phosphorylation	Ccnb1	IDA		Mouse	PMID:12124778
Biological Process	GO:0065003	protein-containing complex assembly	Ccnb1	IDA		Rat	PMID:19136513\|RGD:2316317
Biological Process	GO:0051726	regulation of cell cycle	Ccnb1	IEP		Rat	PMID:8123599\|RGD:1299843
Biological Process	GO:0060623	regulation of chromosome condensation	Ccnb1	IMP		Rat	PMID:15291744\|RGD:1578405
Biological Process	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	CCNB1	IMP		Human	PMID:18195732
Biological Process	GO:0046680	response to DDT	Ccnb1	IEP		Rat	PMID:17984292\|RGD:2316321
Biological Process	GO:0009612	response to mechanical stimulus	Ccnb1	IEP		Rat	PMID:15040886\|RGD:2315995
Biological Process	GO:0009636	response to toxic substance	Ccnb1	IEP		Rat	PMID:16919876\|RGD:2315988
Biological Process	GO:0009410	response to xenobiotic stimulus	Ccnb1	IEP		Rat	PMID:16426843\|RGD:2315989
Biological Process	GO:0007283	spermatogenesis	Ccnb1	IEP		Rat	PMID:11139145\|RGD:2315996
Biological Process	GO:0042246	tissue regeneration	Ccnb1	IEP		Rat	PMID:8123599\|RGD:1299843
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Ccnb1	IEP		Rat	PMID:15253691\|RGD:2301353

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.