Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCND3
  • Mouse genes Ccnd3
  • Rat genes Ccnd3
  • Zfish genes ccnd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccnd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	CCND3	IDA		Human	PMID:8114739
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	Ccnd3	IDA		Mouse	PMID:12130539
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:11896535
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:14641107
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q5VK71	Human	PMID:14641107
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P46527	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q5VK71	Human	PMID:16721056
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:O94921	Human	PMID:17517622
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:17517622
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:19237555
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00535	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00535	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9BT43	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P46527	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00535	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9BT43	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9UBB9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P29373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P55273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00535	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00536-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q07002	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q8IYE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q8NEH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9BT43	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P38936	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P46527	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:Q00535	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P11802	Human	PMID:9106657
Molecular Function	GO:0005515	protein binding	CCND3	IPI	UniProtKB:P08393	Human	PMID:9311810
Molecular Function	GO:0005515	protein binding	Ccnd3	IPI	UniProtKB:Q64261	Mouse	MGI:MGI:5514446|PMID:23948297
Molecular Function	GO:0005515	protein binding	Ccnd3	IPI	UniProtKB:Q64261	Mouse	MGI:MGI:5463835|PMID:23079656
Molecular Function	GO:0005515	protein binding	Ccnd3	IPI	PR:P46414	Mouse	PMID:8033213
Molecular Function	GO:0005515	protein binding	Ccnd3	IPI	PR:P30285	Mouse	PMID:26657864
Molecular Function	GO:0005515	protein binding	Ccnd3	IPI	PR:Q61026	Mouse	PMID:12130539
Molecular Function	GO:0019901	protein kinase binding	CCND3	IPI	UniProtKB:Q00534	Human	PMID:8114739
Molecular Function	GO:0019901	protein kinase binding	Ccnd3	IPI	PR:P30285	Mouse	PMID:23109711
Molecular Function	GO:0019901	protein kinase binding	Ccnd3	IPI	RGD:621120	Rat	PMID:15809057|RGD:1582338
Molecular Function	GO:0019901	protein kinase binding	Ccnd3	IPI	RGD:621121	Rat	PMID:15809057|RGD:1582338
Cellular Component	GO:0097130	cyclin D3-CDK4 complex	CCND3	IPI		Human	PMID:19237555
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	CCND3	IDA		Human	PMID:8114739
Cellular Component	GO:0005737	cytoplasm	Ccnd3	IDA		Mouse	PMID:26657864
Cellular Component	GO:0005654	nucleoplasm	CCND3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ccnd3	IDA		Mouse	PMID:26657864
Cellular Component	GO:0005634	nucleus	Ccnd3	IDA		Mouse	PMID:21539824
Cellular Component	GO:0005634	nucleus	Ccnd3	IDA		Mouse	PMID:23109711
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	CCND3	IDA		Human	PMID:8114739
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Ccnd3	IEP		Rat	PMID:7926809|RGD:724624
Biological Process	GO:0030213	hyaluronan biosynthetic process	Ccnd3	IMP		Rat	PMID:19276076|RGD:2316018
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ccnd3	IDA		Mouse	PMID:23109711
Biological Process	GO:0008284	positive regulation of cell population proliferation	Ccnd3	IMP		Rat	PMID:14576819|RGD:1582343
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	CCND3	IDA		Human	PMID:8114739
Biological Process	GO:0001934	positive regulation of protein phosphorylation	CCND3	IDA		Human	PMID:8114739
Biological Process	GO:0051726	regulation of cell cycle	Ccnd3	IDA		Mouse	PMID:11809706
Biological Process	GO:0042127	regulation of cell population proliferation	Ccnd3	IMP		Mouse	PMID:23109711
Biological Process	GO:0046626	regulation of insulin receptor signaling pathway	Ccnd3	IGI	MGI:MGI:88357	Mouse	PMID:26657864
Biological Process	GO:0009749	response to glucose	Ccnd3	IEP		Rat	PMID:19276076|RGD:2316018
Biological Process	GO:0010033	response to organic substance	Ccnd3	IEP		Rat	PMID:14690525|RGD:2316021
Biological Process	GO:0043434	response to peptide hormone	Ccnd3	IMP		Rat	PMID:14576819|RGD:1582343
Biological Process	GO:0007165	signal transduction	Ccnd3	IDA		Mouse	PMID:12130539
Biological Process	GO:0042098	T cell proliferation	Ccnd3	IMP	MGI:MGI:2448172	Mouse	PMID:14706337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern