Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCR1
  • Mouse genes Ccr1
  • Rat genes Ccr1
  • Zfish genes cabz01093075.1,ccr11.1,ccr2,ccr8.1,si:cabz01093077.1,si:ch211-207g17.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ccr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P10147	Human	PMID:10660125
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P55773	Human	PMID:10660125
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P10147	Human	PMID:15764707
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P10147	Human	PMID:7545673
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P13236	Human	PMID:7545673
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P10147	Human	PMID:8699119
Molecular Function	GO:0019957	C-C chemokine binding	CCR1	IPI	UniProtKB:P13236	Human	PMID:8699119
Molecular Function	GO:0019957	C-C chemokine binding	Ccr1	IDA		Rat	PMID:11091494|RGD:5688180
Molecular Function	GO:0016493	C-C chemokine receptor activity	CCR1	IDA		Human	PMID:10734056
Molecular Function	GO:0016493	C-C chemokine receptor activity	Ccr1	IDA		Mouse	PMID:7594543
Molecular Function	GO:0071791	chemokine (C-C motif) ligand 5 binding	CCR1	IPI	UniProtKB:P13501	Human	PMID:10660125
Molecular Function	GO:0071791	chemokine (C-C motif) ligand 5 binding	CCR1	IPI	UniProtKB:P13501	Human	PMID:10734056
Molecular Function	GO:0071791	chemokine (C-C motif) ligand 5 binding	CCR1	IPI	UniProtKB:P13501	Human	PMID:7545673
Molecular Function	GO:0071791	chemokine (C-C motif) ligand 5 binding	CCR1	IPI	UniProtKB:P13501	Human	PMID:8699119
Molecular Function	GO:0035717	chemokine (C-C motif) ligand 7 binding	CCR1	IPI	UniProtKB:P80098	Human	PMID:10660125
Molecular Function	GO:0035717	chemokine (C-C motif) ligand 7 binding	CCR1	IPI	UniProtKB:P80098	Human	PMID:7545673
Molecular Function	GO:0004950	chemokine receptor activity	CCR1	IDA		Human	PMID:10660125
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	CCR1	IDA		Human	PMID:10734056
Molecular Function	GO:0005515	protein binding	CCR1	IPI	UniProtKB:O43889-2	Human	PMID:15001559
Molecular Function	GO:0005515	protein binding	CCR1	IPI	UniProtKB:Q04941	Human	PMID:15474493
Molecular Function	GO:0005515	protein binding	CCR1	IPI	UniProtKB:P13501	Human	PMID:28381538
Molecular Function	GO:0005515	protein binding	CCR1	IPI	UniProtKB:Q9H3N1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCR1	IPI	UniProtKB:P51681	Human	PMID:8699119
Molecular Function	GO:0005515	protein binding	Ccr1	IPI	PR:P14097	Mouse	PMID:7594543
Molecular Function	GO:0005515	protein binding	Ccr1	IPI	PR:P10148	Mouse	PMID:8631787
Molecular Function	GO:0005515	protein binding	Ccr1	IPI	PR:P10855	Mouse	PMID:7594543
Cellular Component	GO:0009897	external side of plasma membrane	CCR1	IDA		Human	PMID:10706735
Cellular Component	GO:0043025	neuronal cell body	Ccr1	IDA		Rat	PMID:15764707|RGD:5688181
Cellular Component	GO:0005886	plasma membrane	CCR1	IDA		Human	PMID:10660125
Cellular Component	GO:0005886	plasma membrane	CCR1	IMP		Human	PMID:15001559
Cellular Component	GO:0005886	plasma membrane	CCR1	IDA		Human	PMID:15474493
Cellular Component	GO:0005886	plasma membrane	CCR1	IDA		Human	PMID:18587271
Biological Process	GO:0006816	calcium ion transport	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0007267	cell-cell signaling	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Ccr1	IEP		Rat	PMID:23110133|RGD:151665477
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Ccr1	IEP		Rat	PMID:23110133|RGD:151665477
Biological Process	GO:0021549	cerebellum development	Ccr1	IEP		Rat	PMID:12541321|RGD:5688179
Biological Process	GO:0070098	chemokine-mediated signaling pathway	CCR1	IDA		Human	PMID:21403648
Biological Process	GO:0006887	exocytosis	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0006955	immune response	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0006954	inflammatory response	Ccr1	IMP	MGI:MGI:1931850	Mouse	PMID:9166425
Biological Process	GO:0006954	inflammatory response	Ccr1	IEP		Rat	PMID:12144807|RGD:2303104
Biological Process	GO:0006874	intracellular calcium ion homeostasis	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0030595	leukocyte chemotaxis	Ccr1	IMP	MGI:MGI:1931850	Mouse	PMID:9166425
Biological Process	GO:0030595	leukocyte chemotaxis	Ccr1	IDA		Mouse	PMID:7594543
Biological Process	GO:0042117	monocyte activation	ccr2	IMP	ZFIN:ZDB-MRPHLNO-171025-3	Zfish	PMID:28844797
Biological Process	GO:0030099	myeloid cell differentiation	Ccr1	IMP	MGI:MGI:1931850	Mouse	PMID:9166425
Biological Process	GO:0030502	negative regulation of bone mineralization	CCR1	IMP		Human	PMID:21403648
Biological Process	GO:0010629	negative regulation of gene expression	CCR1	IMP		Human	PMID:21403648
Biological Process	GO:0045824	negative regulation of innate immune response	Ccr1	IMP		Mouse	MGI:MGI:4943412|PMID:15557190
Biological Process	GO:0030316	osteoclast differentiation	Ccr1	HEP		Rat	PMID:16304045|RGD:151665775
Biological Process	GO:0051928	positive regulation of calcium ion transport	CCR1	IDA		Human	PMID:15764707
Biological Process	GO:0030335	positive regulation of cell migration	CCR1	IMP		Human	PMID:24056371
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	CCR1	IDA		Human	PMID:10734056
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	CCR1	IMP		Human	PMID:21403648
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	CCR1	IDA		Human	PMID:18587271
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	CCR1	IMP		Human	PMID:21403648

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern