Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCT2
  • Mouse genes Cct2
  • Rat genes Cct2
  • Zfish genes cct2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cct2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q96M98	Human	PMID:14532270
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P17987	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P17987	Human	PMID:16097032
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q9H2J4	Human	PMID:17429077
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8IWZ6	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8IWZ6	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:O60232	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q9BUR4	Human	PMID:25467444
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8NFG4	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q99832	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P17987	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P50991	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q99832	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:O60232	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P50991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:C9J082	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:O14744	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:O43493-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8N0U8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8TAB7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q8TAS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q9UMY4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CCT2	IPI	UniProtKB:Q9Y238	Human	PMID:33144677
Molecular Function	GO:0044183	protein folding chaperone	CCT2	IDA		Human	PMID:25467444
Molecular Function	GO:0044183	protein folding chaperone	CCT2	IDA		Human	PMID:30955883
Molecular Function	GO:0031625	ubiquitin protein ligase binding	CCT2	IPI	UniProtKB:O60260	Human	PMID:21753002
Cellular Component	GO:0044297	cell body	Cct2	IDA		Mouse	PMID:21880732
Cellular Component	GO:0005832	chaperonin-containing T-complex	CCT2	IPI		Human	PMID:22133715
Cellular Component	GO:0005832	chaperonin-containing T-complex	CCT2	IDA		Human	PMID:23011926
Cellular Component	GO:0005832	chaperonin-containing T-complex	CCT2	IDA		Human	PMID:25467444
Cellular Component	GO:0005832	chaperonin-containing T-complex	CCT2	IDA		Human	PMID:30955883
Cellular Component	GO:0005832	chaperonin-containing T-complex	Cct2	IDA		Mouse	PMID:7953530
Cellular Component	GO:0005832	chaperonin-containing T-complex	Cct2	IDA		Mouse	PMID:7828721
Cellular Component	GO:0005829	cytosol	CCT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CCT2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CCT2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CCT2	HDA		Human	PMID:23533145
Cellular Component	GO:0005874	microtubule	CCT2	IDA		Human	PMID:21525035
Cellular Component	GO:0043209	myelin sheath	Cct2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0002199	zona pellucida receptor complex	Cct2	IDA		Mouse	PMID:21880732
Biological Process	GO:0007339	binding of sperm to zona pellucida	Cct2	IDA		Mouse	PMID:21880732
Biological Process	GO:0051086	chaperone mediated protein folding independent of cofactor	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	CCT2	IMP		Human	PMID:20080638
Biological Process	GO:0061077	chaperone-mediated protein folding	CCT2	IDA		Human	PMID:22133715
Biological Process	GO:0070121	Kupffer's vesicle development	cct2	IMP		Zfish	PMID:20080638
Biological Process	GO:0032402	melanosome transport	cct2	IMP		Zfish	PMID:20080638
Biological Process	GO:1904851	positive regulation of establishment of protein localization to telomere	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:1904871	positive regulation of protein localization to Cajal body	CCT2	HMP		Human	PMID:25467444
Biological Process	GO:0051973	positive regulation of telomerase activity	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:1904874	positive regulation of telomerase RNA localization to Cajal body	CCT2	HMP		Human	PMID:25467444
Biological Process	GO:1904874	positive regulation of telomerase RNA localization to Cajal body	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:0006457	protein folding	CCT2	IDA		Human	PMID:30955883
Biological Process	GO:0050821	protein stabilization	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:0090666	scaRNA localization to Cajal body	CCT2	IMP		Human	PMID:25467444
Biological Process	GO:1901998	toxin transport	Cct2	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern