Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD109
  • Mouse genes Cd109
  • Rat genes Cd109
  • Zfish genes cd109
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd109

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050431	transforming growth factor beta binding	CD109	IPI	UniProtKB:P01137	Human	PMID:16754747
Cellular Component	GO:0009986	cell surface	CD109	HDA		Human	PMID:19581412
Cellular Component	GO:0005829	cytosol	CD109	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	Cd109	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005886	plasma membrane	CD109	IDA		Human	GO_REF:0000052
Biological Process	GO:0001942	hair follicle development	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22846721
Biological Process	GO:0043616	keratinocyte proliferation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22846721
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22846721
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22490868
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22846721
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	CD109	IDA		Human	PMID:16754747
Biological Process	GO:0061045	negative regulation of wound healing	CD109	IDA		Human	PMID:16754747
Biological Process	GO:0072675	osteoclast fusion	Cd109	IMP		Mouse	PMID:23593435
Biological Process	GO:0006468	protein phosphorylation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22490868
Biological Process	GO:0045616	regulation of keratinocyte differentiation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22490868
Biological Process	GO:0072089	stem cell proliferation	Cd109	IMP	MGI:MGI:5443927	Mouse	PMID:22846721

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern