Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD14
  • Mouse genes Cd14
  • Rat genes Cd14
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001530	lipopolysaccharide binding	CD14	IDA		Human	PMID:12594207
Molecular Function	GO:0001875	lipopolysaccharide immune receptor activity	CD14	IDA		Human	PMID:15294986
Molecular Function	GO:0070891	lipoteichoic acid binding	CD14	IDA		Human	PMID:12594207
Molecular Function	GO:0060090	molecular adaptor activity	CD14	IDA		Human	PMID:1698311
Molecular Function	GO:0005515	protein binding	CD14	IPI	UniProtKB:O60603,UniProtKB:P16671,UniProtKB:Q9Y2C9	Human	PMID:16880211
Molecular Function	GO:0005515	protein binding	CD14	IPI	UniProtKB:O60603,UniProtKB:Q15399	Human	PMID:16880211
Molecular Function	GO:0005515	protein binding	CD14	IPI	UniProtKB:Q12841	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	CD14	IPI	UniProtKB:Q12841	Human	PMID:22265692
Molecular Function	GO:0005515	protein binding	CD14	IPI	UniProtKB:Q92614	Human	PMID:25965346
Molecular Function	GO:0005515	protein binding	Cd14	IPI	RGD:3870	Rat	PMID:18787027|RGD:2313387
Cellular Component	GO:0009986	cell surface	Cd14	IDA		Rat	PMID:12046090|RGD:724637
Cellular Component	GO:0009897	external side of plasma membrane	CD14	IDA		Human	PMID:3385210
Cellular Component	GO:0009897	external side of plasma membrane	Cd14	IDA		Mouse	MGI:MGI:80217|PMID:8612135
Cellular Component	GO:0009897	external side of plasma membrane	Cd14	IDA		Mouse	PMID:19299737
Cellular Component	GO:0070062	extracellular exosome	CD14	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CD14	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CD14	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CD14	IDA		Human	PMID:7537731
Cellular Component	GO:0005615	extracellular space	CD14	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Cd14	IDA		Rat	PMID:12835948|RGD:2313388
Cellular Component	GO:0005794	Golgi apparatus	CD14	IDA		Human	PMID:16880211
Cellular Component	GO:0046696	lipopolysaccharide receptor complex	CD14	IDA		Human	PMID:11274165
Cellular Component	GO:0045121	membrane raft	CD14	IDA		Human	PMID:16880211
Cellular Component	GO:0045121	membrane raft	Cd14	IDA		Mouse	MGI:MGI:3759338|PMID:15493995
Cellular Component	GO:0005886	plasma membrane	Cd14	IDA		Rat	PMID:18787027|RGD:2313387
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	CD14	IDA		Human	PMID:15294986
Biological Process	GO:0071726	cellular response to diacyl bacterial lipopeptide	CD14	IDA		Human	PMID:16880211
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CD14	IDA		Human	PMID:12594207
Biological Process	GO:0071222	cellular response to lipopolysaccharide	CD14	IMP		Human	PMID:8612135
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cd14	IMP		Mouse	MGI:MGI:80217|PMID:8612135
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cd14	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cd14	IEP		Rat	PMID:22511970|RGD:7183752
Biological Process	GO:0071223	cellular response to lipoteichoic acid	CD14	IDA		Human	PMID:12594207
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	CD14	IDA		Human	PMID:15039339
Biological Process	GO:0071727	cellular response to triacyl bacterial lipopeptide	CD14	IDA		Human	PMID:16880211
Biological Process	GO:0006954	inflammatory response	Cd14	IDA		Rat	PMID:12218159|RGD:727423
Biological Process	GO:0001819	positive regulation of cytokine production	Cd14	IMP		Rat	PMID:12046090|RGD:724637
Biological Process	GO:0045807	positive regulation of endocytosis	Cd14	IMP		Mouse	MGI:MGI:5300392|PMID:22078883
Biological Process	GO:0032757	positive regulation of interleukin-8 production	CD14	IMP		Human	PMID:15039339
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	Cd14	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	Cd14	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	CD14	IDA		Human	PMID:12594207
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	CD14	IMP		Human	PMID:8612135
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Cd14	IMP		Mouse	MGI:MGI:80217|PMID:8612135
Biological Process	GO:0032481	positive regulation of type I interferon production	Cd14	IMP		Mouse	MGI:MGI:5300392|PMID:22078883
Biological Process	GO:0032729	positive regulation of type II interferon production	Cd14	IMP		Mouse	MGI:MGI:5645195|PMID:24380872
Biological Process	GO:0006898	receptor-mediated endocytosis	Cd14	IMP		Mouse	MGI:MGI:5300392|PMID:22078883
Biological Process	GO:0009617	response to bacterium	Cd14	IMP		Mouse	MGI:MGI:80217|PMID:8612135
Biological Process	GO:0009617	response to bacterium	Cd14	IEP		Mouse	PMID:23012479
Biological Process	GO:0051602	response to electrical stimulus	Cd14	IEP		Rat	PMID:19464360|RGD:2313386
Biological Process	GO:0045471	response to ethanol	Cd14	IEP		Rat	PMID:10414605|RGD:7204127
Biological Process	GO:0009408	response to heat	Cd14	IEP		Rat	PMID:12435950|RGD:2313390
Biological Process	GO:0032496	response to lipopolysaccharide	Cd14	IEP		Rat	PMID:16631199|RGD:2313381
Biological Process	GO:0032026	response to magnesium ion	Cd14	IEP		Rat	PMID:16180088|RGD:7191759
Biological Process	GO:0002237	response to molecule of bacterial origin	Cd14	IDA		Mouse	MGI:MGI:3759338|PMID:15493995
Biological Process	GO:0034612	response to tumor necrosis factor	Cd14	IMP		Rat	PMID:10777809|RGD:7193332
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	CD14	IDA		Human	PMID:27986454

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern