Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD1D
  • Mouse genes Cd1d1
  • Rat genes Cd1d1
  • Zfish genes mhc1laa,mhc1lba,mhc1lca,mhc1lga,mhc1lla,si:dkey-52p2.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd1d1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	CD1D	IPI	UniProtKB:Q8N423	Human	PMID:19124746
Molecular Function	GO:0030883	endogenous lipid antigen binding	Cd1d1	IDA		Mouse	PMID:14722359
Molecular Function	GO:0030884	exogenous lipid antigen binding	CD1D	IDA		Human	PMID:10523605
Molecular Function	GO:0042393	histone binding	CD1D	IPI	UniProtKB:Q13547	Human	PMID:20363964
Molecular Function	GO:0030882	lipid antigen binding	CD1D	IDA		Human	PMID:19124746
Molecular Function	GO:0030882	lipid antigen binding	CD1D	IDA		Human	PMID:21802320
Molecular Function	GO:0005515	protein binding	CD1D	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	Cd1d1	IPI	PR:P04441-2	Mouse	PMID:11754812
Molecular Function	GO:0042608	T cell receptor binding	Cd1d1	IDA		Mouse	PMID:22065767
Cellular Component	GO:0009986	cell surface	CD1D	IDA		Human	PMID:19124746
Cellular Component	GO:0005737	cytoplasm	CD1D	IDA		Human	PMID:19124746
Cellular Component	GO:0005769	early endosome	Cd1d1	IDA		Mouse	PMID:11754812
Cellular Component	GO:0005783	endoplasmic reticulum	CD1D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	Cd1d1	IDA		Mouse	PMID:9133426
Cellular Component	GO:0009897	external side of plasma membrane	Cd1d1	IDA		Mouse	PMID:10201995
Cellular Component	GO:0009897	external side of plasma membrane	Cd1d1	IDA		Mouse	PMID:17082577
Cellular Component	GO:0009897	external side of plasma membrane	Cd1d1	IDA		Mouse	PMID:14557411
Cellular Component	GO:0009897	external side of plasma membrane	Cd1d1	IDA		Mouse	PMID:11754812
Cellular Component	GO:0005770	late endosome	Cd1d1	IDA		Mouse	PMID:11754812
Cellular Component	GO:0005764	lysosome	CD1D	IDA		Human	PMID:21802320
Cellular Component	GO:0005764	lysosome	Cd1d1	IDA		Mouse	PMID:14557411
Cellular Component	GO:0005764	lysosome	Cd1d1	IDA		Mouse	PMID:11754812
Biological Process	GO:0019882	antigen processing and presentation	Cd1d1	IDA		Mouse	PMID:11754812
Biological Process	GO:0048006	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	CD1D	IDA		Human	PMID:10523605
Biological Process	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	Cd1d1	IDA		Mouse	PMID:14557411
Biological Process	GO:0001865	NK T cell differentiation	Cd1d1	IMP		Mouse	MGI:MGI:87097|PMID:9133426
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd1d1	IDA		Mouse	PMID:10201995
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd1d1	IDA		Mouse	PMID:7538697
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd1d1	IDA		Mouse	PMID:11754812
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd1d1	IDA		Mouse	PMID:14557411
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Cd1d1	IMP	MGI:MGI:2180713	Mouse	PMID:10201995
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Cd1d1	IDA		Mouse	PMID:7538697
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Cd1d1	IMP	MGI:MGI:2180711	Mouse	PMID:9133426
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Cd1d1	IDA		Mouse	PMID:11754812
Biological Process	GO:0043032	positive regulation of macrophage activation	Cd1d1	IDA		Mouse	PMID:21460847
Biological Process	GO:0051135	positive regulation of NK T cell activation	Cd1d1	IDA		Mouse	PMID:10201995
Biological Process	GO:0051135	positive regulation of NK T cell activation	Cd1d1	IDA		Mouse	PMID:7538697
Biological Process	GO:0051135	positive regulation of NK T cell activation	Cd1d1	IDA		Mouse	PMID:11754812
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	Cd1d1	IMP	MGI:MGI:2180713	Mouse	PMID:10201995
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	Cd1d1	IMP	MGI:MGI:2180711	Mouse	PMID:9133426
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	Cd1d1	IDA		Mouse	PMID:10201995
Biological Process	GO:0042102	positive regulation of T cell proliferation	CD1D	IDA		Human	PMID:19124746
Biological Process	GO:0032729	positive regulation of type II interferon production	Cd1d1	IMP	MGI:MGI:2180711	Mouse	PMID:9133426
Biological Process	GO:0045059	positive thymic T cell selection	Cd1d1	IMP	MGI:MGI:2180711	Mouse	PMID:9133426
Biological Process	GO:0033084	regulation of immature T cell proliferation in thymus	Cd1d1	IMP		Mouse	MGI:MGI:3759394|PMID:11550008
Biological Process	GO:0050776	regulation of immune response	Cd1d1	IMP	MGI:MGI:2180711	Mouse	PMID:9133426

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern