Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD2
  • Mouse genes Cd2
  • Rat genes Cd2
  • Zfish genes si:dkey-11f4.20
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Cd2	IPI	PR:P08920	Mouse	PMID:1383383
Molecular Function	GO:0042802	identical protein binding	Cd2	IPI	RGD:2297	Rat	PMID:10526406|RGD:1625378
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:P19256	Human	PMID:10380930
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:P09326	Human	PMID:12356317
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:O95400	Human	PMID:15105431
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:O95400	Human	PMID:16000308
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:Q9Y5K6	Human	PMID:17020880
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:P08575	Human	PMID:1970422
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:P08637	Human	PMID:23006327
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:Q96B97	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:Q9Y5K6	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:P19256	Human	PMID:7544493
Molecular Function	GO:0005515	protein binding	CD2	IPI	UniProtKB:O95400	Human	PMID:9843987
Molecular Function	GO:0005515	protein binding	Cd2	IPI	PR:P18181	Mouse	PMID:1383383
Molecular Function	GO:0005515	protein binding	Cd2	IPI	RGD:2309	Rat	PMID:11981840|RGD:634711
Molecular Function	GO:0005515	protein binding	Cd2	IPI	RGD:620620	Rat	PMID:9576909|RGD:1625383
Molecular Function	GO:0019901	protein kinase binding	Cd2	IPI	RGD:2641	Rat	PMID:1280324|RGD:2324895
Molecular Function	GO:0043621	protein self-association	Cd2	IDA		Rat	PMID:10841761|RGD:1625376
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Cd2	IPI	RGD:2994	Rat	PMID:18178839|RGD:2316555
Molecular Function	GO:0005102	signaling receptor binding	CD2	IPI	UniProtKB:P19256	Human	PMID:17344209
Cellular Component	GO:0009986	cell surface	CD2	IDA		Human	PMID:15345303
Cellular Component	GO:0009986	cell surface	Cd2	IDA		Rat	PMID:11981840|RGD:634711
Cellular Component	GO:0009986	cell surface	Cd2	IDA		Rat	PMID:8938183|RGD:1625386
Cellular Component	GO:0005911	cell-cell junction	Cd2	IDA		Mouse	PMID:23793062
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Cd2	IDA		Mouse	PMID:1383383
Cellular Component	GO:0009897	external side of plasma membrane	CD2	IDA		Human	PMID:21460847
Cellular Component	GO:0009897	external side of plasma membrane	Cd2	IDA		Mouse	PMID:8125140
Cellular Component	GO:0009897	external side of plasma membrane	Cd2	IDA		Mouse	PMID:12874832
Cellular Component	GO:0005576	extracellular region	Cd2	IDA		Mouse	PMID:1383383
Cellular Component	GO:0005794	Golgi apparatus	CD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045121	membrane raft	Cd2	IDA		Rat	PMID:18178839|RGD:2316555
Cellular Component	GO:0005654	nucleoplasm	CD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CD2	IDA		Human	PMID:23006327
Cellular Component	GO:0005886	plasma membrane	Cd2	IDA		Mouse	PMID:1383383
Cellular Component	GO:0032991	protein-containing complex	Cd2	IDA		Rat	PMID:9576909|RGD:1625383
Biological Process	GO:0098609	cell-cell adhesion	Cd2	IMP		Rat	PMID:8938183|RGD:1625386
Biological Process	GO:0034113	heterotypic cell-cell adhesion	CD2	IDA		Human	PMID:15345303
Biological Process	GO:0030101	natural killer cell activation	CD2	IDA		Human	PMID:23006327
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	CD2	IDA		Human	PMID:23006327
Biological Process	GO:0032757	positive regulation of interleukin-8 production	CD2	IMP		Human	PMID:19109405
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	CD2	IDA		Human	PMID:19109405
Biological Process	GO:0032729	positive regulation of type II interferon production	CD2	IDA		Human	PMID:19109405
Biological Process	GO:0042110	T cell activation	Cd2	IMP		Rat	PMID:10458478|RGD:1625382

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern