Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD200
  • Mouse genes Cd200
  • Rat genes Cd200
  • Zfish genes sc:d189,zgc:113337,zgc:172122
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd200

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CD200	IPI	UniProtKB:Q8TD46	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	Cd200	IPI	UniProtKB:Q9ES57	Mouse	MGI:MGI:5926662|PMID:23602662
Molecular Function	GO:0005515	protein binding	Cd200	IPI	PR:Q6XJV4	Mouse	PMID:15274657
Molecular Function	GO:0005515	protein binding	Cd200	IPI	PR:Q6XJV6	Mouse	PMID:15274657
Molecular Function	GO:0005515	protein binding	Cd200	IPI	PR:Q5UKY4	Mouse	PMID:15274657
Molecular Function	GO:0005515	protein binding	Cd200	IPI	PR:Q9ES57	Mouse	PMID:15274657
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	Cd200	IPI	UniProtKB:Q9ES58	Rat	PMID:10981966|RGD:61663
Cellular Component	GO:0030424	axon	CD200	IDA		Human	PMID:19151626
Cellular Component	GO:0044297	cell body	CD200	IDA		Human	PMID:19151626
Cellular Component	GO:0009986	cell surface	CD200	IDA		Human	PMID:11260322
Cellular Component	GO:0009986	cell surface	Cd200	IDA		Mouse	MGI:MGI:1927692|PMID:11099416
Cellular Component	GO:0009986	cell surface	Cd200	IDA		Rat	PMID:10981966|RGD:61663
Cellular Component	GO:0009986	cell surface	Cd200	IDA		Rat	PMID:18164423|RGD:13792521
Cellular Component	GO:0043005	neuron projection	Cd200	IDA		Rat	PMID:6147390|RGD:13702371
Cellular Component	GO:0043025	neuronal cell body	CD200	IDA		Human	PMID:19151626
Cellular Component	GO:0043025	neuronal cell body	Cd200	IDA		Rat	PMID:6147390|RGD:13702371
Biological Process	GO:0098609	cell-cell adhesion	Cd200	IGI	UniProtKB:P05540	Rat	PMID:9295026|RGD:13792541
Biological Process	GO:0034113	heterotypic cell-cell adhesion	CD200	IGI	UniProtKB:P05540	Human	PMID:11260322
Biological Process	GO:0034113	heterotypic cell-cell adhesion	Cd200	IPI	UniProtKB:Q9ES58	Rat	PMID:10981966|RGD:61663
Biological Process	GO:0034113	heterotypic cell-cell adhesion	Cd200	IGI	UniProtKB:P05540	Rat	PMID:9295026|RGD:13792541
Biological Process	GO:0008285	negative regulation of cell population proliferation	Cd200	IMP		Mouse	MGI:MGI:1927692|PMID:11099416
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:18164423|RGD:13792521
Biological Process	GO:0043031	negative regulation of macrophage activation	Cd200	IMP		Mouse	MGI:MGI:1927692|PMID:11099416
Biological Process	GO:1905522	negative regulation of macrophage migration	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:18164423|RGD:13792521
Biological Process	GO:1904465	negative regulation of matrix metallopeptidase secretion	CD200	IDA		Human	PMID:29101312
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	Cd200	IMP		Mouse	MGI:MGI:1927692|PMID:11099416
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:18164423|RGD:13792521
Biological Process	GO:1901215	negative regulation of neuron death	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:18164423|RGD:13792521
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	CD200	IDA		Human	PMID:26670206
Biological Process	GO:2000405	negative regulation of T cell migration	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:18164423|RGD:13792521
Biological Process	GO:0150072	positive regulation of arginase activity	CD200	IGI	UniProtKB:P21272	Human	PMID:26670206
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	CD200	IDA		Human	PMID:26670206
Biological Process	GO:0150074	positive regulation of protein-glutamine gamma-glutamyltransferase activity	CD200	IGI	UniProtKB:P21272	Human	PMID:26670206
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	CD200	IGI	UniProtKB:P21272	Human	PMID:26670206
Biological Process	GO:0150077	regulation of neuroinflammatory response	Cd200	IGI	UniProtKB:Q9ES58	Rat	PMID:10981966|RGD:61663

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern