Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cd2ap

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CD2AP
- Mouse genes Cd2ap
- Rat genes Cd2ap
- Zfish genes cd2ap
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd2ap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Cd2ap	IDA		Rat	PMID:16617054\|RGD:1582382
Molecular Function	GO:0045296	cadherin binding	CD2AP	HDA		Human	PMID:25468996
Molecular Function	GO:0045296	cadherin binding	Cd2ap	IPI	RGD:69279	Rat	PMID:15910750\|RGD:1582380
Molecular Function	GO:0045296	cadherin binding	Cd2ap	IPI	RGD:69280	Rat	PMID:16617054\|RGD:1582382
Molecular Function	GO:0042802	identical protein binding	CD2AP	IPI	UniProtKB:Q9Y5K6	Human	PMID:17020880
Molecular Function	GO:0042802	identical protein binding	CD2AP	IPI	UniProtKB:Q9Y5K6	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q6P5Z4	Human	PMID:10339567
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P06729	Human	PMID:17020880
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P22681	Human	PMID:17020880
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q13191	Human	PMID:17020880
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P06241	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q8WUM4	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q99816	Human	PMID:17853893
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q8WUM4	Human	PMID:18641129
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P62993	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q8WV28	Human	PMID:21822214
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P62993	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P46940	Human	PMID:22662192
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P52907	Human	PMID:22891260
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q9Y3L3	Human	PMID:22891260
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P06729	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q13191	Human	PMID:23663663
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P22681	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q96B97	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:P06241	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q8WUM4	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q96B97	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q96B97	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	CD2AP	IPI	UniProtKB:Q8TB24	Human	PMID:32552912
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	UniProtKB:P22682	Mouse	MGI:MGI:5758812\|PMID:12559036
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	UniProtKB:P22682	Mouse	MGI:MGI:5825410\|PMID:27474268
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	PR:O35245	Mouse	PMID:10913159
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	RGD:1316966	Rat	PMID:15001553\|RGD:1302417
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	RGD:1306305	Rat	PMID:16617054\|RGD:1582382
Molecular Function	GO:0005515	protein binding	Cd2ap	IPI	RGD:621842	Rat	PMID:16617054\|RGD:1582382
Molecular Function	GO:0044877	protein-containing complex binding	Cd2ap	IPI	RGD:3852\|RGD:1306216	Rat	PMID:16617054\|RGD:1582382
Molecular Function	GO:0017124	SH3 domain binding	CD2AP	IPI	UniProtKB:P56945	Human	PMID:10339567
Molecular Function	GO:0005172	vascular endothelial growth factor receptor binding	Cd2ap	IDA		Rat	PMID:15001553\|RGD:1302417
Cellular Component	GO:0030424	axon	Cd2ap	IDA		Mouse	MGI:MGI:6478068\|PMID:32552912
Cellular Component	GO:0031252	cell leading edge	Cd2ap	IDA		Rat	PMID:15910750\|RGD:1582380
Cellular Component	GO:0005911	cell-cell junction	Cd2ap	IDA		Mouse	PMID:23793062
Cellular Component	GO:0034451	centriolar satellite	CD2AP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Cd2ap	IDA		Mouse	PMID:10913159
Cellular Component	GO:0030425	dendrite	Cd2ap	IDA		Mouse	MGI:MGI:6478068\|PMID:32552912
Cellular Component	GO:0030139	endocytic vesicle	Cd2ap	IDA		Rat	PMID:15001553\|RGD:1302417
Cellular Component	GO:0070062	extracellular exosome	CD2AP	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CD2AP	HDA		Human	PMID:23533145
Cellular Component	GO:0001650	fibrillar center	CD2AP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031941	filamentous actin	CD2AP	IDA		Human	PMID:10339567
Cellular Component	GO:0031594	neuromuscular junction	Cd2ap	IDA		Mouse	PMID:31412248
Cellular Component	GO:0031594	neuromuscular junction	Cd2ap	IEP		Mouse	PMID:31412248
Cellular Component	GO:0031594	neuromuscular junction	Cd2ap	IPI		Mouse	PMID:31412248
Cellular Component	GO:0031594	neuromuscular junction	Cd2ap	IMP		Mouse	PMID:31412248
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cd2ap	IDA		Rat	PMID:15910750\|RGD:1582380
Cellular Component	GO:0005886	plasma membrane	CD2AP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Cd2ap	IDA		Mouse	PMID:15924139
Cellular Component	GO:0032991	protein-containing complex	Cd2ap	IDA		Rat	PMID:16617054\|RGD:1582382
Cellular Component	GO:0001726	ruffle	CD2AP	IDA		Human	PMID:10339567
Cellular Component	GO:0031982	vesicle	Cd2ap	IDA		Mouse	MGI:MGI:6478068\|PMID:32552912
Biological Process	GO:0007015	actin filament organization	CD2AP	IMP		Human	PMID:22891260
Biological Process	GO:0016477	cell migration	Cd2ap	IMP		Rat	PMID:15910750\|RGD:1582380
Biological Process	GO:0098609	cell-cell adhesion	Cd2ap	IMP		Rat	PMID:16617054\|RGD:1582382
Biological Process	GO:0003094	glomerular filtration	cd2ap	IMP	ZFIN:ZDB-MRPHLNO-071114-1	Zfish	PMID:25962121
Biological Process	GO:0032835	glomerulus development	cd2ap	IMP	ZFIN:ZDB-MRPHLNO-071114-1	Zfish	PMID:17699558
Biological Process	GO:0051058	negative regulation of small GTPase mediated signal transduction	CD2AP	IMP		Human	PMID:22891260
Biological Process	GO:0032911	negative regulation of transforming growth factor beta1 production	Cd2ap	IGI	MGI:MGI:98725	Mouse	PMID:21911934
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	Cd2ap	IGI	MGI:MGI:98725	Mouse	PMID:21911934
Biological Process	GO:0050714	positive regulation of protein secretion	CD2AP	IMP		Human	PMID:27044754
Biological Process	GO:0039021	pronephric glomerulus development	cd2ap	IMP	ZFIN:ZDB-MRPHLNO-071114-1	Zfish	PMID:27441654
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Cd2ap	IDA		Rat	PMID:15001553\|RGD:1302417
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Cd2ap	IGI	MGI:MGI:98725	Mouse	PMID:21911934
Biological Process	GO:0048259	regulation of receptor-mediated endocytosis	Cd2ap	IDA		Rat	PMID:15001553\|RGD:1302417
Biological Process	GO:0050808	synapse organization	Cd2ap	IMP		Mouse	PMID:31412248
Biological Process	GO:0050808	synapse organization	Cd2ap	IPI		Mouse	PMID:31412248
Biological Process	GO:0050808	synapse organization	Cd2ap	IDA		Mouse	PMID:31412248
Biological Process	GO:0050808	synapse organization	Cd2ap	IEP		Mouse	PMID:31412248
Biological Process	GO:0032905	transforming growth factor beta1 production	Cd2ap	IGI	MGI:MGI:98725	Mouse	PMID:21911934
Biological Process	GO:0016050	vesicle organization	Cd2ap	IDA		Rat	PMID:15001553\|RGD:1302417

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.