Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD34
  • Mouse genes Cd34
  • Rat genes Cd34
  • Zfish genes cd34,si:ch211-286o17.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd34

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	CD34	IDA		Human	PMID:15249540
Molecular Function	GO:0005515	protein binding	CD34	IPI	UniProtKB:O95994	Human	PMID:32296183
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	CD34	IPI	UniProtKB:Q01196	Human	PMID:21873977
Molecular Function	GO:0043199	sulfate binding	Cd34	IDA		Mouse	PMID:14597732
Cellular Component	GO:0016324	apical plasma membrane	Cd34	IDA		Rat	PMID:18319274|RGD:8553277
Cellular Component	GO:0009925	basal plasma membrane	Cd34	IDA		Rat	PMID:18319274|RGD:8553277
Cellular Component	GO:0071944	cell periphery	Cd34	IDA		Mouse	PMID:21464233
Cellular Component	GO:0009986	cell surface	Cd34	IDA		Mouse	MGI:MGI:4410397|PMID:19833765
Cellular Component	GO:0009986	cell surface	Cd34	IDA		Mouse	PMID:9324354
Cellular Component	GO:0005737	cytoplasm	CD34	IDA		Human	PMID:7525669
Cellular Component	GO:0005737	cytoplasm	Cd34	IDA		Mouse	PMID:17717145
Cellular Component	GO:0009897	external side of plasma membrane	CD34	IDA		Human	PMID:10337918
Cellular Component	GO:0009897	external side of plasma membrane	CD34	IDA		Human	PMID:12939361
Cellular Component	GO:0009897	external side of plasma membrane	CD34	IDA		Human	PMID:20354148
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:10943842
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:12714519
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:21708977
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:17882221
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:12900455
Cellular Component	GO:0009897	external side of plasma membrane	Cd34	IDA		Mouse	PMID:19360001
Cellular Component	GO:0005576	extracellular region	Cd34	IDA		Mouse	PMID:14597732
Cellular Component	GO:0036053	glomerular endothelium fenestra	Cd34	IDA		Rat	PMID:18319274|RGD:8553277
Cellular Component	GO:0045171	intercellular bridge	CD34	IDA		Human	PMID:7525669
Cellular Component	GO:0005764	lysosome	Cd34	IDA		Rat	PMID:18319274|RGD:8553277
Cellular Component	GO:0016020	membrane	Cd34	IDA		Mouse	PMID:17717145
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CD34	IDA		Human	PMID:7525669
Cellular Component	GO:0005886	plasma membrane	CD34	IDA		Human	PMID:17464107
Cellular Component	GO:0005886	plasma membrane	CD34	IDA		Human	PMID:1868864
Cellular Component	GO:0005886	plasma membrane	CD34	IDA		Human	PMID:7525669
Cellular Component	GO:0005886	plasma membrane	CD34	IDA		Human	PMID:9042286
Cellular Component	GO:0005886	plasma membrane	Cd34	IDA		Rat	PMID:18319274|RGD:8553277
Biological Process	GO:0048870	cell motility	CD34	IEP		Human	PMID:17261663
Biological Process	GO:0098609	cell-cell adhesion	CD34	IDA		Human	PMID:15249540
Biological Process	GO:0001935	endothelial cell proliferation	CD34	IDA		Human	PMID:21835908
Biological Process	GO:0003158	endothelium development	CD34	IEP		Human	PMID:17261663
Biological Process	GO:0071971	extracellular exosome assembly	CD34	IDA		Human	PMID:21835908
Biological Process	GO:0072011	glomerular endothelium development	CD34	IEP		Human	PMID:17464107
Biological Process	GO:0003094	glomerular filtration	CD34	IEP		Human	PMID:20354148
Biological Process	GO:0003094	glomerular filtration	Cd34	IEP		Rat	PMID:18319274|RGD:8553277
Biological Process	GO:0071425	hematopoietic stem cell proliferation	CD34	IMP		Human	PMID:21873977
Biological Process	GO:0030097	hemopoiesis	CD34	IMP		Human	PMID:15969628
Biological Process	GO:0050900	leukocyte migration	Cd34	IMP		Mouse	PMID:15701716
Biological Process	GO:0035759	mesangial cell-matrix adhesion	Cd34	IEP		Rat	PMID:18319274|RGD:8553277
Biological Process	GO:0072254	metanephric glomerular mesangial cell differentiation	CD34	IEP		Human	PMID:1868864
Biological Process	GO:0030195	negative regulation of blood coagulation	CD34	IDA		Human	PMID:17505307
Biological Process	GO:1900035	negative regulation of cellular response to heat	CD34	IDA		Human	PMID:17505307
Biological Process	GO:1900038	negative regulation of cellular response to hypoxia	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0010629	negative regulation of gene expression	CD34	IMP		Human	PMID:15969628
Biological Process	GO:0032703	negative regulation of interleukin-2 production	CD34	IMP		Human	PMID:9815891
Biological Process	GO:1901215	negative regulation of neuron death	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0038001	paracrine signaling	CD34	IDA		Human	PMID:21835908
Biological Process	GO:0045766	positive regulation of angiogenesis	CD34	IDA		Human	PMID:12939361
Biological Process	GO:0045766	positive regulation of angiogenesis	CD34	IDA		Human	PMID:21835908
Biological Process	GO:0010628	positive regulation of gene expression	CD34	IEP		Human	PMID:17261663
Biological Process	GO:1900168	positive regulation of glial cell-derived neurotrophic factor production	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0071657	positive regulation of granulocyte colony-stimulating factor production	CD34	IEP		Human	PMID:17261663
Biological Process	GO:0071657	positive regulation of granulocyte colony-stimulating factor production	CD34	IDA		Human	PMID:9815891
Biological Process	GO:0032733	positive regulation of interleukin-10 production	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0042482	positive regulation of odontogenesis	CD34	IDA		Human	PMID:12939361
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	CD34	IDA		Human	PMID:17505307
Biological Process	GO:2001214	positive regulation of vasculogenesis	CD34	IDA		Human	PMID:12939361
Biological Process	GO:0008217	regulation of blood pressure	CD34	IDA		Human	PMID:17505307
Biological Process	GO:0007165	signal transduction	CD34	IEP		Human	PMID:17261663
Biological Process	GO:0072089	stem cell proliferation	CD34	IEP		Human	PMID:17261663
Biological Process	GO:0001894	tissue homeostasis	CD34	IDA		Human	PMID:12939361
Biological Process	GO:0060290	transdifferentiation	CD34	IEP		Human	PMID:1868864
Biological Process	GO:0061042	vascular wound healing	CD34	IEP		Human	PMID:20354148

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern