Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD38
  • Mouse genes Cd38
  • Rat genes Cd38
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd38

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	Cd38	IMP	MGI:MGI:1861803	Mouse	PMID:12403647
Molecular Function	GO:0042802	identical protein binding	Cd38	IPI	UniProtKB:P56528	Mouse	MGI:MGI:5927356|PMID:22863568
Molecular Function	GO:0003953	NAD+ nucleosidase activity	Cd38	IDA		Rat	PMID:11733184|RGD:1299847
Molecular Function	GO:0016849	phosphorus-oxygen lyase activity	Cd38	IMP	MGI:MGI:1861803	Mouse	PMID:12403647
Cellular Component	GO:0016323	basolateral plasma membrane	Cd38	IDA		Rat	PMID:21784055|RGD:13506922
Cellular Component	GO:0009986	cell surface	Cd38	IDA		Mouse	PMID:9324354
Cellular Component	GO:0009986	cell surface	Cd38	IDA		Mouse	PMID:16493007
Cellular Component	GO:0070062	extracellular exosome	CD38	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cd38	IDA		Rat	PMID:11733184|RGD:1299847
Cellular Component	GO:0016020	membrane	Cd38	IDA		Mouse	PMID:12403647
Cellular Component	GO:0005634	nucleus	Cd38	IDA		Rat	PMID:11733184|RGD:1299847
Cellular Component	GO:0005886	plasma membrane	CD38	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Cd38	IDA		Rat	PMID:17200192|RGD:2307238
Cellular Component	GO:0030667	secretory granule membrane	Cd38	IDA		Rat	PMID:21784055|RGD:13506922
Biological Process	GO:0014824	artery smooth muscle contraction	Cd38	IMP		Rat	PMID:21431168|RGD:13506923
Biological Process	GO:0042100	B cell proliferation	Cd38	IDA		Mouse	PMID:8666928
Biological Process	GO:0050853	B cell receptor signaling pathway	CD38	IMP		Human	PMID:17875758
Biological Process	GO:0007565	female pregnancy	Cd38	IEP		Rat	PMID:14998907|RGD:2307240
Biological Process	GO:0060292	long-term synaptic depression	Cd38	IMP		Rat	PMID:10097163|RGD:2307271
Biological Process	GO:0043066	negative regulation of apoptotic process	CD38	IMP		Human	PMID:17875758
Biological Process	GO:0045779	negative regulation of bone resorption	Cd38	IDA		Rat	PMID:10477767|RGD:2307268
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CD38	IMP		Human	PMID:17875758
Biological Process	GO:0010977	negative regulation of neuron projection development	Cd38	IMP		Rat	PMID:19696022|RGD:13506924
Biological Process	GO:0030890	positive regulation of B cell proliferation	CD38	IMP		Human	PMID:17875758
Biological Process	GO:0030890	positive regulation of B cell proliferation	Cd38	IDA		Mouse	PMID:8666928
Biological Process	GO:0030307	positive regulation of cell growth	Cd38	IMP		Rat	PMID:18719074|RGD:2307236
Biological Process	GO:0008284	positive regulation of cell population proliferation	Cd38	IMP		Rat	PMID:19696022|RGD:13506924
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Cd38	IMP		Rat	PMID:18719074|RGD:2307236
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CD38	IMP		Human	PMID:17875758
Biological Process	GO:0032024	positive regulation of insulin secretion	Cd38	IMP		Rat	PMID:9664081|RGD:2307276
Biological Process	GO:0045907	positive regulation of vasoconstriction	Cd38	IMP		Rat	PMID:18524860|RGD:2307237
Biological Process	GO:0034097	response to cytokine	Cd38	IEP		Rat	PMID:11399650|RGD:2307263
Biological Process	GO:0032355	response to estradiol	Cd38	IEP		Rat	PMID:14998907|RGD:2307240
Biological Process	GO:0009725	response to hormone	Cd38	IDA		Rat	PMID:9325179|RGD:2307277
Biological Process	GO:0033194	response to hydroperoxide	Cd38	IDA		Rat	PMID:12893282|RGD:2307242
Biological Process	GO:0001666	response to hypoxia	Cd38	IDA		Rat	PMID:12111041|RGD:2307243
Biological Process	GO:0070555	response to interleukin-1	Cd38	IEP		Rat	PMID:11399650|RGD:2307263
Biological Process	GO:0032570	response to progesterone	Cd38	IEP		Rat	PMID:14998907|RGD:2307240
Biological Process	GO:0032526	response to retinoic acid	Cd38	IEP		Rat	PMID:11399650|RGD:2307263
Biological Process	GO:0009410	response to xenobiotic stimulus	CD38	IMP		Human	PMID:17875758

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern