Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD70
  • Mouse genes Cd70
  • Rat genes Cd70
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd70

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	CD70	IMP		Human	PMID:28011863
Molecular Function	GO:0005125	cytokine activity	CD70	IMP		Human	PMID:28011864
Molecular Function	GO:0002020	protease binding	CD70	IPI	UniProtKB:P78325	Human	PMID:12777399
Molecular Function	GO:0005515	protein binding	CD70	IPI	UniProtKB:P26842	Human	PMID:12324477
Molecular Function	GO:0005515	protein binding	CD70	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	CD70	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	CD70	IDA		Human	PMID:11920585
Biological Process	GO:0019724	B cell mediated immunity	CD70	IMP		Human	PMID:28011863
Biological Process	GO:0019724	B cell mediated immunity	CD70	IMP		Human	PMID:28011864
Biological Process	GO:0042100	B cell proliferation	CD70	IMP		Human	PMID:28011863
Biological Process	GO:0042100	B cell proliferation	CD70	IMP		Human	PMID:28011864
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	CD70	IDA		Human	PMID:9177220
Biological Process	GO:0002456	T cell mediated immunity	CD70	IMP		Human	PMID:28011863
Biological Process	GO:0002456	T cell mediated immunity	CD70	IMP		Human	PMID:28011864

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern