Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD80
  • Mouse genes Cd80
  • Rat genes Cd80
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd80

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:P16410	Human	PMID:11279502
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:Q9NZQ7	Human	PMID:18585785
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:P16410	Human	PMID:20587542
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:Q9NZQ7	Human	PMID:20587542
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:P08138	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:P16410	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:Q9NZQ7	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:Q9NZQ7	Human	PMID:23417675
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:Q9NZQ7	Human	PMID:31000591
Molecular Function	GO:0005515	protein binding	CD80	IPI	UniProtKB:P10747	Human	PMID:9915850
Molecular Function	GO:0005515	protein binding	Cd80	IPI	UniProtKB:Q9EP73	Mouse	MGI:MGI:6189321|PMID:23417675
Molecular Function	GO:0005515	protein binding	Cd80	IPI	UniProtKB:Q9EP73	Mouse	MGI:MGI:6315984|PMID:31000591
Molecular Function	GO:0005515	protein binding	Cd80	IPI	UniProtKB:Q9EP73	Mouse	MGI:MGI:5315328|PMID:21884581
Molecular Function	GO:0005515	protein binding	Cd80	IPI	UniProtKB:P10747	Mouse	PMID:1385153
Molecular Function	GO:0005515	protein binding	Cd80	IPI	UniProtKB:O95653	Mouse	PMID:1385153
Molecular Function	GO:0048018	receptor ligand activity	CD80	IDA		Human	PMID:24845157
Cellular Component	GO:0009986	cell surface	CD80	HDA		Human	PMID:23981064
Cellular Component	GO:0009986	cell surface	Cd80	IDA		Rat	PMID:15474526|RGD:151665813
Cellular Component	GO:0009986	cell surface	Cd80	IDA		Rat	PMID:18589158|RGD:4892226
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:1385153
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:15240714
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:15314074
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:18684012
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:8566034
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:14560001
Cellular Component	GO:0009897	external side of plasma membrane	Cd80	IDA		Mouse	PMID:15568026
Cellular Component	GO:0098636	protein complex involved in cell adhesion	CD80	IDA		Human	PMID:7544393
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cd80	IDA		Mouse	PMID:19047410
Biological Process	GO:0002710	negative regulation of T cell mediated immunity	CD80	IDA		Human	PMID:11015443
Biological Process	GO:0046641	positive regulation of alpha-beta T cell proliferation	Cd80	IDA		Mouse	PMID:1385153
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	CD80	IDA		Human	PMID:9915850
Biological Process	GO:0042102	positive regulation of T cell proliferation	Cd80	IGI	MGI:MGI:101773	Mouse	PMID:23793062
Biological Process	GO:0042102	positive regulation of T cell proliferation	Cd80	IMP		Rat	PMID:9237108|RGD:632472
Biological Process	GO:0042110	T cell activation	CD80	IDA		Human	PMID:23918985
Biological Process	GO:0031295	T cell costimulation	Cd80	IDA		Mouse	PMID:1385153
Biological Process	GO:0031295	T cell costimulation	Cd80	IDA		Mouse	PMID:15568026

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern