Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD83
  • Mouse genes Cd83
  • Rat genes Cd83
  • Zfish genes cd83
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd83

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CD83	IPI	UniProtKB:O52302	Human	PMID:20374249
Molecular Function	GO:0005515	protein binding	CD83	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	cd83	IDA		Zfish	PMID:25445909
Cellular Component	GO:0009897	external side of plasma membrane	Cd83	IDA		Mouse	PMID:15322158
Cellular Component	GO:0071753	IgM immunoglobulin complex	cd83	IDA		Zfish	PMID:24532580
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0002468	dendritic cell antigen processing and presentation	cd83	IDA		Zfish	PMID:25445909
Biological Process	GO:0032613	interleukin-10 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0032623	interleukin-2 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0032633	interleukin-4 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0032713	negative regulation of interleukin-4 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0032733	positive regulation of interleukin-10 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0014070	response to organic cyclic compound	Cd83	IMP	MGI:MGI:3055293	Mouse	PMID:15322158
Biological Process	GO:0002286	T cell activation involved in immune response	cd83	IDA		Zfish	PMID:25445909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern