Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD84
  • Mouse genes Cd84
  • Rat genes Cd84
  • Zfish genes si:cabz01074946.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd84

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CD84	IPI	UniProtKB:Q9UIB8	Human	PMID:17563375
Molecular Function	GO:0005515	protein binding	CD84	IPI	UniProtKB:O14796	Human	PMID:12928397
Molecular Function	GO:0005515	protein binding	CD84	IPI	UniProtKB:O14796	Human	PMID:23322602
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CD84	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CD84	IDA		Human	GO_REF:0000052
Biological Process	GO:0032685	negative regulation of granulocyte macrophage colony-stimulating factor production	CD84	IDA		Human	PMID:22068234
Biological Process	GO:0032693	negative regulation of interleukin-10 production	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0032701	negative regulation of interleukin-18 production	CD84	IDA		Human	PMID:22068234
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0033004	negative regulation of mast cell activation	CD84	IDA		Human	PMID:22068234
Biological Process	GO:0043305	negative regulation of mast cell degranulation	CD84	IDA		Human	PMID:22068234
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:0043030	regulation of macrophage activation	Cd84	IDA		Mouse	MGI:MGI:5700297|PMID:20628063
Biological Process	GO:2001256	regulation of store-operated calcium entry	CD84	IDA		Human	PMID:22068234

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern