Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CD8B,CD8B2
  • Mouse genes Cd8b1
  • Rat genes Cd8b
  • Zfish genes cd8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cd8b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CD8B	IPI	UniProtKB:P01732	Human	PMID:2493728
Molecular Function	GO:0005515	protein binding	Cd8b1	IPI	UniProtKB:P04235	Mouse	MGI:MGI:3687904|PMID:12215456
Cellular Component	GO:0009986	cell surface	Cd8b1	IDA		Mouse	PMID:14568922
Cellular Component	GO:0009897	external side of plasma membrane	Cd8b1	IDA		Mouse	PMID:1673361
Cellular Component	GO:0009897	external side of plasma membrane	Cd8b1	IDA		Mouse	PMID:15294943
Cellular Component	GO:0009897	external side of plasma membrane	Cd8b1	IDA		Mouse	PMID:7589135
Cellular Component	GO:0009897	external side of plasma membrane	Cd8b1	IDA		Mouse	PMID:10704459
Cellular Component	GO:0005886	plasma membrane	CD8B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043235	receptor complex	Cd8b1	IPI		Mouse	MGI:MGI:6810793|PMID:22081144
Biological Process	GO:0042110	T cell activation	CD8B	IDA		Human	PMID:17145893
Biological Process	GO:0050852	T cell receptor signaling pathway	CD8B	IDA		Human	PMID:17145893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern