Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC25A
  • Mouse genes Cdc25a
  • Rat genes Cdc25a
  • Zfish genes cdc25b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc25a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Cdc25a	IDA		Rat	PMID:10373478|RGD:724654
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:O96017	Human	PMID:11298456
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P27348	Human	PMID:19289404
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P27348	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P31946	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:Q9BSU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P04049	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	CDC25A	IPI	UniProtKB:P31946	Human	PMID:7644510
Molecular Function	GO:0019901	protein kinase binding	CDC25A	IPI	UniProtKB:Q9H4B4	Human	PMID:21376736
Molecular Function	GO:0051087	protein-folding chaperone binding	CDC25A	IPI	UniProtKB:P07900|UniProtKB:P08238	Human	PMID:22843495
Cellular Component	GO:0005737	cytoplasm	Cdc25a	IDA		Mouse	PMID:11981756
Cellular Component	GO:0005737	cytoplasm	Cdc25a	IDA		Rat	PMID:15139290|RGD:1601462
Cellular Component	GO:0005634	nucleus	Cdc25a	IDA		Mouse	PMID:11981756
Cellular Component	GO:0005634	nucleus	Cdc25a	IDA		Rat	PMID:15139290|RGD:1601462
Biological Process	GO:0034644	cellular response to UV	CDC25A	IDA		Human	PMID:19966869
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Cdc25a	IMP		Rat	PMID:8156993|RGD:724653
Biological Process	GO:1904056	positive regulation of cholangiocyte proliferation	Cdc25a	IMP		Rat	PMID:22155366|RGD:14700990
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-GENO-140610-2	Zfish	PMID:24478331
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-MRPHLNO-131125-9	Zfish	PMID:22986406
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-GENO-131126-2	Zfish	PMID:22986406
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-MRPHLNO-131125-8	Zfish	PMID:22986406
Biological Process	GO:0009794	regulation of mitotic cell cycle, embryonic	cdc25b	IMP		Zfish	PMID:19063878
Biological Process	GO:0009314	response to radiation	CDC25A	IDA		Human	PMID:21376736

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern