Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC25C
  • Mouse genes Cdc25c
  • Rat genes Cdc25c
  • Zfish genes cdc25b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc25c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:O14757	Human	PMID:11836499
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P27448	Human	PMID:12941695
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:O14757	Human	PMID:16330544
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P53350	Human	PMID:17307877
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P06493	Human	PMID:17349584
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:Q9Y250	Human	PMID:17349584
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P31946	Human	PMID:19470455
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P53350	Human	PMID:19597481
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P31946	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P06493	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P31946	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P63104	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P31946	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	CDC25C	IPI	UniProtKB:P63104	Human	PMID:9543386
Molecular Function	GO:0005515	protein binding	Cdc25c	IPI	PR:Q9CQV8	Mouse	PMID:12937170
Molecular Function	GO:0005515	protein binding	Cdc25c	IPI	RGD:69308	Rat	PMID:17374997|RGD:2313457
Molecular Function	GO:0019901	protein kinase binding	CDC25C	IPI	UniProtKB:Q9H4B4	Human	PMID:14968113
Molecular Function	GO:0019901	protein kinase binding	CDC25C	IPI	UniProtKB:P27448	Human	PMID:9543386
Molecular Function	GO:0050699	WW domain binding	CDC25C	IPI	UniProtKB:Q13526	Human	PMID:10037602
Cellular Component	GO:0005737	cytoplasm	Cdc25c	IDA		Mouse	PMID:12937170
Cellular Component	GO:0005758	mitochondrial intermembrane space	Cdc25c	IDA		Mouse	PMID:25002142
Cellular Component	GO:0005634	nucleus	CDC25C	IDA		Human	PMID:14968113
Cellular Component	GO:0005634	nucleus	Cdc25c	IDA		Mouse	PMID:12937170
Cellular Component	GO:0005634	nucleus	Cdc25c	IDA		Rat	PMID:9166700|RGD:2313458
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cdc25c	IDA		Rat	PMID:17374997|RGD:2313457
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	CDC25C	IGI	UniProtKB:P06652	Human	PMID:2195549
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-GENO-140610-2	Zfish	PMID:24478331
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-MRPHLNO-131125-9	Zfish	PMID:22986406
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-GENO-131126-2	Zfish	PMID:22986406
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	cdc25b	IMP	ZFIN:ZDB-MRPHLNO-131125-8	Zfish	PMID:22986406
Biological Process	GO:0009794	regulation of mitotic cell cycle, embryonic	cdc25b	IMP		Zfish	PMID:19063878
Biological Process	GO:0007283	spermatogenesis	Cdc25c	IEP		Rat	PMID:9166700|RGD:2313458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern