Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC34
  • Mouse genes Cdc34b
  • Rat genes Cdc34
  • Zfish genes cdc34a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc34b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:Q03060-11	Human	PMID:10373550
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:Q9Y2D1	Human	PMID:10373550
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:Q13616	Human	PMID:19945379
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC34	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	CDC34	IDA		Human	PMID:20061386
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	CDC34	IDA		Human	PMID:10373550
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	CDC34	IDA		Human	PMID:20061386
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	CDC34	IDA		Human	PMID:20347421
Cellular Component	GO:0005829	cytosol	CDC34	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CDC34	IDA		Human	GO_REF:0000052
Biological Process	GO:0035458	cellular response to interferon-beta	CDC34	IMP		Human	PMID:24882218
Biological Process	GO:0043951	negative regulation of cAMP-mediated signaling	CDC34	IDA		Human	PMID:10373550
Biological Process	GO:0090261	positive regulation of inclusion body assembly	Cdc34	IMP		Rat	PMID:12401444|RGD:2316159
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Cdc34	IMP		Rat	PMID:12401444|RGD:2316159
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	CDC34	IDA		Human	PMID:10373550
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	CDC34	IDA		Human	PMID:20347421
Biological Process	GO:0070936	protein K48-linked ubiquitination	CDC34	IDA		Human	PMID:20061386
Biological Process	GO:0000209	protein polyubiquitination	CDC34	IDA		Human	PMID:20347421
Biological Process	GO:0016567	protein ubiquitination	CDC34	IDA		Human	PMID:10373550
Biological Process	GO:0070848	response to growth factor	Cdc34	IEP		Rat	PMID:15037588|RGD:2316158

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern