Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC40
  • Mouse genes Cdc40
  • Rat genes Cdc40
  • Zfish genes cdc40
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc40

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC40	IPI	UniProtKB:Q9UMS4	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	CDC40	IPI	UniProtKB:Q9UMS4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDC40	IPI	UniProtKB:Q9Y3C6	Human	PMID:33220177
Molecular Function	GO:0003723	RNA binding	CDC40	HDA		Human	PMID:22658674
Cellular Component	GO:0071013	catalytic step 2 spliceosome	CDC40	IDA		Human	PMID:11991638
Cellular Component	GO:0016607	nuclear speck	CDC40	IDA		Human	PMID:9830021
Cellular Component	GO:0005654	nucleoplasm	CDC40	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071007	U2-type catalytic step 2 spliceosome	CDC40	IDA		Human	PMID:28076346
Biological Process	GO:1990403	embryonic brain development	CDC40	IMP		Human	PMID:33220177
Biological Process	GO:0000398	mRNA splicing, via spliceosome	CDC40	IDA		Human	PMID:28076346
Biological Process	GO:0000398	mRNA splicing, via spliceosome	CDC40	IMP		Human	PMID:33220177

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern