Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC42EP4
  • Mouse genes Cdc42ep4
  • Rat genes Cdc42ep4
  • Zfish genes cdc42ep4a,cdc42ep4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc42ep4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC42EP4	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC42EP4	IPI	UniProtKB:Q8IZU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDC42EP4	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cdc42ep4	IPI	PR:Q8R527	Mouse	PMID:10490598
Molecular Function	GO:0003723	RNA binding	CDC42EP4	HDA		Human	PMID:22658674
Cellular Component	GO:0015629	actin cytoskeleton	CDC42EP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005912	adherens junction	CDC42EP4	IDA		Human	PMID:25468996
Cellular Component	GO:0005737	cytoplasm	Cdc42ep4	IDA		Mouse	PMID:10490598
Cellular Component	GO:0015630	microtubule cytoskeleton	CDC42EP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045335	phagocytic vesicle	Cdc42ep4	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	CDC42EP4	IDA		Human	GO_REF:0000052
Biological Process	GO:0071346	cellular response to type II interferon	Cdc42ep4	IDA		Mouse	PMID:19144319
Biological Process	GO:0031274	positive regulation of pseudopodium assembly	CDC42EP4	IDA		Human	PMID:11035016
Biological Process	GO:0008360	regulation of cell shape	CDC42EP4	IDA		Human	PMID:11035016
Biological Process	GO:0007266	Rho protein signal transduction	Cdc42ep4	IDA		Mouse	PMID:10490598

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern