Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC5L
  • Mouse genes Cdc5l
  • Rat genes Cdc5l
  • Zfish genes cdc5l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc5l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CDC5L	IDA		Human	PMID:11082045
Molecular Function	GO:0042802	identical protein binding	CDC5L	IPI	UniProtKB:Q99459	Human	PMID:20176811
Molecular Function	GO:0042802	identical protein binding	CDC5L	IPI	UniProtKB:Q99459	Human	PMID:20467437
Molecular Function	GO:0043522	leucine zipper domain binding	Cdc5l	IPI	RGD:621766	Rat	PMID:11884640|RGD:619664
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UNY4	Human	PMID:12927788
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q13416	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O60341	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q01082	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q7Z3B3	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q96KQ4	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UJC3	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q15428	Human	PMID:17332742
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8WYA6	Human	PMID:18722174
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q13535	Human	PMID:19633697
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UMS4	Human	PMID:19633697
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O43660	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O75934	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8WYA6	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UMS4	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O43660	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O60341	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O75934	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P07910	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P52272	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P62136	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q01082	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q13416	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q15428	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q7Z3B3	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UMS4	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O75934	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P62136	Human	PMID:22940584
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9BQ65	Human	PMID:23022480
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8WYA6	Human	PMID:24269683
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q08AF8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q0D2H9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UMS4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O75934	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P07910	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O60341	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q01082	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q7Z3B3	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q96KQ4	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UJC3	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:O95751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P40222	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q05BL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8N3V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q96KQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:Q9UJC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC5L	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cdc5l	IPI	UniProtKB:Q9JMJ4	Rat	PMID:16352598|RGD:10047232
Molecular Function	GO:0019901	protein kinase binding	Cdc5l	IPI	RGD:621766	Rat	PMID:11884640|RGD:619664
Molecular Function	GO:0008157	protein phosphatase 1 binding	Cdc5l	IPI	RGD:1306280	Rat	PMID:10827081|RGD:10045998
Molecular Function	GO:0003723	RNA binding	CDC5L	HDA		Human	PMID:22681889
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	CDC5L	IDA		Human	PMID:11082045
Molecular Function	GO:0001222	transcription corepressor binding	Cdc5l	IPI	RGD:61998	Rat	PMID:20629186|RGD:10045890
Molecular Function	GO:0071987	WD40-repeat domain binding	CDC5L	IDA		Human	PMID:20176811
Cellular Component	GO:0071013	catalytic step 2 spliceosome	CDC5L	IDA		Human	PMID:11991638
Cellular Component	GO:0005737	cytoplasm	CDC5L	IDA		Human	PMID:9038199
Cellular Component	GO:0016020	membrane	CDC5L	HDA		Human	PMID:19946888
Cellular Component	GO:0016607	nuclear speck	CDC5L	IDA		Human	PMID:16332694
Cellular Component	GO:0016607	nuclear speck	Cdc5l	IDA		Rat	PMID:11884640|RGD:619664
Cellular Component	GO:0005654	nucleoplasm	CDC5L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDC5L	IDA		Human	PMID:20176811
Cellular Component	GO:0005634	nucleus	CDC5L	IDA		Human	PMID:28076346
Cellular Component	GO:0005634	nucleus	Cdc5l	IDA		Rat	PMID:11884640|RGD:619664
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cdc5l	IDA		Rat	PMID:11694351|RGD:10047049
Cellular Component	GO:0032993	protein-DNA complex	Cdc5l	IDA		Rat	PMID:11694351|RGD:10047049
Cellular Component	GO:0000974	Prp19 complex	CDC5L	IPI		Human	PMID:20176811
Cellular Component	GO:0000974	Prp19 complex	CDC5L	IDA		Human	PMID:20176811
Cellular Component	GO:0005681	spliceosomal complex	CDC5L	IPI		Human	PMID:20176811
Cellular Component	GO:0071007	U2-type catalytic step 2 spliceosome	CDC5L	IDA		Human	PMID:28076346
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Cdc5l	IEP		Rat	PMID:11694351|RGD:10047049
Biological Process	GO:0071352	cellular response to interleukin-2	Cdc5l	IEP		Rat	PMID:11694351|RGD:10047049
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Cdc5l	IDA		Rat	PMID:20629186|RGD:10045890
Biological Process	GO:1990646	cellular response to prolactin	Cdc5l	IEP		Rat	PMID:9296381|RGD:61637
Biological Process	GO:1904568	cellular response to wortmannin	Cdc5l	IDA		Rat	PMID:20629186|RGD:10045890
Biological Process	GO:0000077	DNA damage checkpoint signaling	CDC5L	IMP		Human	PMID:24332808
Biological Process	GO:0000278	mitotic cell cycle	Cdc5l	IMP		Rat	PMID:11694351|RGD:10047049
Biological Process	GO:0000398	mRNA splicing, via spliceosome	CDC5L	IDA		Human	PMID:28076346
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDC5L	IDA		Human	PMID:11082045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern