Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDC73
  • Mouse genes Cdc73
  • Rat genes Cdc73
  • Zfish genes cdc73
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdc73

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P24928	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q92541	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P24928	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q92541	Human	PMID:16024656
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:O00512	Human	PMID:16630820
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P35222	Human	PMID:16630820
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:O00512	Human	PMID:17113272
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:O95639	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P33240	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q92541	Human	PMID:20178742
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q03164	Human	PMID:20541477
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:O75031	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8NHQ1	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:A1L4K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P13196	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q9BZW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q9H9H4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:A1L4K1	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P13196	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q08379	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q12800	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q5JR59-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N6L0	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8NHQ1	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q9BZW7	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P24928	Human	PMID:26659056
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q06124	Human	PMID:26742426
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q06124-2	Human	PMID:26742426
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P35222	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q15047	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q6PD62	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8N7H5	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8WVC0	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q96KQ7	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:A1L4K1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P13196	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q15276	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q5VTR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDC73	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cdc73	IPI	UniProtKB:P83870	Mouse	MGI:MGI:6203683|PMID:27749823
Molecular Function	GO:0005515	protein binding	Cdc73	IPI	UniProtKB:Q5XJV7	Mouse	MGI:MGI:5812827|PMID:27864380
Molecular Function	GO:0005515	protein binding	Cdc73	IPI	PR:Q5XJE5	Mouse	PMID:22252316
Molecular Function	GO:0000993	RNA polymerase II complex binding	CDC73	IDA		Human	PMID:15923622
Cellular Component	GO:0016593	Cdc73/Paf1 complex	CDC73	IDA		Human	PMID:16307923
Cellular Component	GO:0016593	Cdc73/Paf1 complex	CDC73	IDA		Human	PMID:18987311
Cellular Component	GO:0016593	Cdc73/Paf1 complex	CDC73	IDA		Human	PMID:20178742
Cellular Component	GO:0016593	Cdc73/Paf1 complex	cdc73	IDA		Zfish	PMID:21338598
Cellular Component	GO:0000781	chromosome, telomeric region	CDC73	HDA		Human	PMID:19135898
Cellular Component	GO:0005829	cytosol	CDC73	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CDC73	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDC73	IDA		Human	PMID:15923622
Cellular Component	GO:0005634	nucleus	cdc73	IDA		Zfish	PMID:21338598
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cdc73	IDA		Mouse	MGI:MGI:5319608|PMID:17911113
Biological Process	GO:0001711	endodermal cell fate commitment	Cdc73	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0030218	erythrocyte differentiation	cdc73	IGI	ZFIN:ZDB-GENO-101021-4	Zfish	PMID:20603019
Biological Process	GO:0007507	heart development	cdc73	IMP		Zfish	PMID:21338598|ZFIN:ZDB-PUB-110316-17
Biological Process	GO:0006378	mRNA polyadenylation	CDC73	IMP		Human	PMID:21329879
Biological Process	GO:0043066	negative regulation of apoptotic process	Cdc73	IMP		Mouse	PMID:18212049
Biological Process	GO:0008285	negative regulation of cell population proliferation	CDC73	IDA		Human	PMID:16989776
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	CDC73	IMP		Human	PMID:18987311
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	CDC73	IMP		Human	PMID:18987311
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	CDC73	IDA		Human	PMID:16989776
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	CDC73	IDA		Human	PMID:20541477
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CDC73	IMP		Human	PMID:18987311
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cdc73	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:1902808	positive regulation of cell cycle G1/S phase transition	CDC73	IMP		Human	PMID:15923622
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	CDC73	IMP		Human	PMID:19136632
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDC73	IDA		Human	PMID:16307923
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	CDC73	IDA		Human	PMID:16630820
Biological Process	GO:0031648	protein destabilization	CDC73	IMP		Human	PMID:18987311
Biological Process	GO:0001558	regulation of cell growth	Cdc73	IMP		Mouse	PMID:18212049
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Cdc73	IMP		Mouse	PMID:18212049
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	cdc73	IGI	ZFIN:ZDB-GENO-101022-4,ZFIN:ZDB-MRPHLNO-100823-6	Zfish	PMID:20603019
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	cdc73	IMP	ZFIN:ZDB-MRPHLNO-120710-2	Zfish	PMID:22699901
Biological Process	GO:0019827	stem cell population maintenance	Cdc73	IMP		Mouse	MGI:MGI:3849235|PMID:19345177
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	CDC73	IDA		Human	PMID:20178742

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern