Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDH3
  • Mouse genes Cdh3
  • Rat genes Cdh3
  • Zfish genes cdh1,cdh28,cdh31
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdh3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	cdh1	IPI	UniProtKB:Q5YKG3	Zfish	PMID:19307601
Cellular Component	GO:0005912	adherens junction	Cdh3	IDA		Mouse	PMID:15775979
Cellular Component	GO:0005912	adherens junction	Cdh3	IDA		Mouse	PMID:15728677
Cellular Component	GO:0005912	adherens junction	cdh1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0016342	catenin complex	cdh1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0005938	cell cortex	cdh1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0030054	cell junction	CDH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Cdh3	IDA		Rat	PMID:17298545|RGD:1600804
Cellular Component	GO:0016020	membrane	cdh1	IDA		Zfish	PMID:17728346
Cellular Component	GO:0016020	membrane	cdh1	IDA		Zfish	PMID:15703282
Cellular Component	GO:0005902	microvillus	cdh1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0005886	plasma membrane	CDH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CDH3	IDA		Human	PMID:10460003
Cellular Component	GO:0005886	plasma membrane	Cdh3	IDA		Mouse	PMID:12060406
Cellular Component	GO:0005886	plasma membrane	Cdh3	IDA		Rat	PMID:17298545|RGD:1600804
Cellular Component	GO:0005886	plasma membrane	cdh1	IDA		Zfish	PMID:19911055
Cellular Component	GO:0005886	plasma membrane	cdh1	IDA		Zfish	PMID:19278297
Biological Process	GO:0034334	adherens junction maintenance	cdh1	IMP	ZFIN:ZDB-MRPHLNO-100423-4	Zfish	PMID:19278297
Biological Process	GO:0007155	cell adhesion	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:23667256
Biological Process	GO:0042074	cell migration involved in gastrulation	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050826-2	Zfish	PMID:15905076
Biological Process	GO:0042074	cell migration involved in gastrulation	cdh1	IMP	ZFIN:ZDB-GENO-150128-7	Zfish	PMID:15905076
Biological Process	GO:0042074	cell migration involved in gastrulation	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:15703282
Biological Process	GO:0042074	cell migration involved in gastrulation	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050310-2	Zfish	PMID:18039968
Biological Process	GO:0042074	cell migration involved in gastrulation	cdh1	IMP	ZFIN:ZDB-GENO-980202-915	Zfish	PMID:15768401
Biological Process	GO:0098609	cell-cell adhesion	Cdh3	IMP		Mouse	PMID:15148305
Biological Process	GO:0098609	cell-cell adhesion	cdh1	IGI	ZFIN:ZDB-GENO-110729-1	Zfish	PMID:19609345
Biological Process	GO:0098609	cell-cell adhesion	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:20079641
Biological Process	GO:0098609	cell-cell adhesion	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:16198297
Biological Process	GO:0098609	cell-cell adhesion	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050826-2	Zfish	PMID:15905076
Biological Process	GO:0070586	cell-cell adhesion involved in gastrulation	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1,ZFIN:ZDB-MRPHLNO-050421-2	Zfish	PMID:19404452
Biological Process	GO:0003370	cell-cell adhesion involved in mesendodermal cell migration	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:20079641
Biological Process	GO:0007398	ectoderm development	cdh1	IMP	ZFIN:ZDB-GENO-980202-915	Zfish	PMID:15768401
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050826-2	Zfish	PMID:19598108
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cdh1	IGI	ZFIN:ZDB-GENO-110729-1	Zfish	PMID:19609345
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cdh1	IGI	ZFIN:ZDB-MRPHLNO-050421-1,ZFIN:ZDB-MRPHLNO-100423-4	Zfish	PMID:19278297
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP		Zfish	PMID:15162505
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050310-2	Zfish	PMID:15689372
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050310-1	Zfish	PMID:15689372
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-GENO-150128-7	Zfish	PMID:15905076
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-MRPHLNO-050826-2	Zfish	PMID:15905076
Biological Process	GO:0001702	gastrulation with mouth forming second	cdh1	IMP	ZFIN:ZDB-GENO-980202-915	Zfish	PMID:15689372
Biological Process	GO:0008354	germ cell migration	cdh1	IMP		Zfish	PMID:16129886
Biological Process	GO:0022405	hair cycle process	CDH3	IMP		Human	PMID:23143461
Biological Process	GO:0031424	keratinization	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0051796	negative regulation of timing of catagen	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0032912	negative regulation of transforming growth factor beta2 production	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0001841	neural tube formation	cdh1	IMP	ZFIN:ZDB-GENO-980202-915	Zfish	PMID:15768401
Biological Process	GO:0001764	neuron migration	cdh1	IMP		Zfish	PMID:16129396
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	CDH3	IMP		Human	PMID:23334344
Biological Process	GO:0010628	positive regulation of gene expression	CDH3	IMP		Human	PMID:23334344
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0048023	positive regulation of melanin biosynthetic process	CDH3	IMP		Human	PMID:23334344
Biological Process	GO:1902910	positive regulation of melanosome transport	CDH3	IMP		Human	PMID:23334344
Biological Process	GO:0032773	positive regulation of tyrosinase activity	CDH3	IMP		Human	PMID:23334344
Biological Process	GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway	CDH3	IMP		Human	PMID:22696062
Biological Process	GO:0009410	response to xenobiotic stimulus	Cdh3	IEP		Rat	PMID:17298545|RGD:1600804
Biological Process	GO:0001895	retina homeostasis	CDH3	IMP		Human	PMID:23143461
Biological Process	GO:0042060	wound healing	Cdh3	IEP		Rat	PMID:15771627|RGD:1600806

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern