Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDHR2
  • Mouse genes Cdhr2
  • Rat genes Cdhr2
  • Zfish genes cdhr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdhr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	CDHR2	IDA		Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR2	IPI	UniProtKB:Q6P0Q8	Human	PMID:12117771
Molecular Function	GO:0005515	protein binding	CDHR2	IPI	UniProtKB:Q6PIF6	Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR2	IPI	UniProtKB:Q9HBB8-1	Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR2	IPI	UniProtKB:Q9HBB8-2	Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR2	IPI	UniProtKB:Q9Y6N9-1	Human	PMID:24725409
Cellular Component	GO:0016324	apical plasma membrane	CDHR2	IDA		Human	PMID:12117771
Cellular Component	GO:0016324	apical plasma membrane	CDHR2	IDA		Human	PMID:24725409
Cellular Component	GO:0005903	brush border	CDHR2	IDA		Human	PMID:21330445
Cellular Component	GO:0031526	brush border membrane	CDHR2	IDA		Human	PMID:24725409
Cellular Component	GO:0070062	extracellular exosome	CDHR2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CDHR2	HDA		Human	PMID:23533145
Cellular Component	GO:0031528	microvillus membrane	CDHR2	IDA		Human	PMID:12117771
Cellular Component	GO:0031528	microvillus membrane	CDHR2	IDA		Human	PMID:24725409
Cellular Component	GO:0005886	plasma membrane	CDHR2	IDA		Human	PMID:24725409
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	CDHR2	IDA		Human	PMID:12117771
Biological Process	GO:0030855	epithelial cell differentiation	CDHR2	IDA		Human	PMID:12117771
Biological Process	GO:0090675	intermicrovillar adhesion	CDHR2	IMP		Human	PMID:24725409
Biological Process	GO:0060243	negative regulation of cell growth involved in contact inhibition	CDHR2	IDA		Human	PMID:12117771
Biological Process	GO:0032532	regulation of microvillus length	CDHR2	IMP		Human	PMID:24725409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern