Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDHR5
  • Mouse genes Cdhr5
  • Rat genes Cdhr5
  • Zfish genes cdhr5a,cdhr5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdhr5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	CDHR5	IPI	UniProtKB:P35222	Human	PMID:22202456
Molecular Function	GO:0005509	calcium ion binding	Cdhr5	IDA		Rat	PMID:10801787|RGD:633361
Molecular Function	GO:0050839	cell adhesion molecule binding	CDHR5	IDA		Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR5	IPI	UniProtKB:Q6PIF6	Human	PMID:24725409
Molecular Function	GO:0005515	protein binding	CDHR5	IPI	UniProtKB:Q9Y6N9-1	Human	PMID:24725409
Cellular Component	GO:0016324	apical plasma membrane	CDHR5	IDA		Human	PMID:24725409
Cellular Component	GO:0031526	brush border membrane	CDHR5	IDA		Human	PMID:24725409
Cellular Component	GO:0005905	clathrin-coated pit	Cdhr5	IDA		Rat	PMID:10801787|RGD:633361
Cellular Component	GO:0070062	extracellular exosome	CDHR5	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CDHR5	HDA		Human	PMID:23533145
Cellular Component	GO:0031528	microvillus membrane	CDHR5	IDA		Human	PMID:24725409
Cellular Component	GO:0005886	plasma membrane	CDHR5	IDA		Human	PMID:24725409
Biological Process	GO:0007155	cell adhesion	Cdhr5	IDA		Rat	PMID:10801787|RGD:633361
Biological Process	GO:0007155	cell adhesion	Cdhr5	IMP		Rat	PMID:10801787|RGD:633361
Biological Process	GO:0090675	intermicrovillar adhesion	CDHR5	IMP		Human	PMID:24725409
Biological Process	GO:0032532	regulation of microvillus length	CDHR5	IMP		Human	PMID:24725409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern