Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK13
  • Mouse genes Cdk13
  • Rat genes Cdk13
  • Zfish genes cdk13
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	CDK13	IPI	UniProtKB:O75909	Human	PMID:22012619
Molecular Function	GO:0030332	cyclin binding	Cdk13	IPI	UniProtKB:Q52KE7|UniProtKB:Q9JJA7	Mouse	MGI:MGI:3699439|PMID:17261272
Molecular Function	GO:0005515	protein binding	CDK13	IPI	UniProtKB:Q07021	Human	PMID:16721827
Molecular Function	GO:0005515	protein binding	CDK13	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	CDK13	IPI	UniProtKB:O75909	Human	PMID:26748711
Molecular Function	GO:0005515	protein binding	CDK13	IPI	UniProtKB:O75909	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK13	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0019901	protein kinase binding	Cdk13	IDA		Mouse	PMID:22547058
Molecular Function	GO:0003723	RNA binding	CDK13	HDA		Human	PMID:22681889
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK13	IDA		Human	PMID:20952539
Cellular Component	GO:0002945	cyclin K-CDK13 complex	CDK13	IPI		Human	PMID:26748711
Cellular Component	GO:0002945	cyclin K-CDK13 complex	CDK13	IPI	UniProtKB:O75909	Human	PMID:22012619
Cellular Component	GO:0005829	cytosol	CDK13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	CDK13	HDA		Human	PMID:22664934
Cellular Component	GO:0005794	Golgi apparatus	CDK13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	Cdk13	IDA		Mouse	MGI:MGI:3699439|PMID:17261272
Cellular Component	GO:0016607	nuclear speck	CDK13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CDK13	IDA		Human	PMID:16721827
Biological Process	GO:0000380	alternative mRNA splicing, via spliceosome	Cdk13	IDA		Mouse	MGI:MGI:3699439|PMID:17261272
Biological Process	GO:0030097	hemopoiesis	CDK13	IMP		Human	PMID:1731328
Biological Process	GO:2000737	negative regulation of stem cell differentiation	Cdk13	IMP		Mouse	PMID:22547058
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDK13	IDA		Human	PMID:20952539
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	CDK13	IDA		Human	PMID:26748711
Biological Process	GO:0009966	regulation of signal transduction	CDK13	IDA		Human	PMID:26748711

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern