Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK16
  • Mouse genes Cdk16
  • Rat genes Cdk16
  • Zfish genes cdk16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q15436	Human	PMID:16091426
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q8N7R7	Human	PMID:22184064
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q8ND76-1	Human	PMID:22184064
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:O43829	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q8N7R7	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q8N7R7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CDK16	IPI	UniProtKB:Q8N7R7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Cdk16	IPI	UniProtKB:Q8BGU5	Mouse	MGI:MGI:5319028|PMID:22184064
Molecular Function	GO:0005515	protein binding	Cdk16	IPI	MGI:MGI:2138614	Mouse	PMID:26305884
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK16	IDA		Human	PMID:22184064
Molecular Function	GO:0004674	protein serine/threonine kinase activity	CDK16	IDA		Human	PMID:22796189
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk16	IMP		Mouse	MGI:MGI:5447616|PMID:16461345
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Cdk16	IDA		Rat	PMID:16461345|RGD:8553541
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	CDK16	IPI		Human	PMID:19524571
Cellular Component	GO:0005737	cytoplasm	CDK16	IDA		Human	PMID:22798068
Cellular Component	GO:0005829	cytosol	CDK16	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	CDK16	IDA		Human	PMID:22184064
Cellular Component	GO:0015630	microtubule cytoskeleton	CDK16	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CDK16	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CDK16	IDA		Human	PMID:19524571
Cellular Component	GO:0008021	synaptic vesicle	Cdk16	IDA		Mouse	MGI:MGI:5447616|PMID:16461345
Cellular Component	GO:0008021	synaptic vesicle	Cdk16	IDA		Rat	PMID:16461345|RGD:8553541
Biological Process	GO:0006887	exocytosis	Cdk16	IMP		Mouse	MGI:MGI:5447616|PMID:16461345
Biological Process	GO:0030252	growth hormone secretion	Cdk16	IMP		Mouse	MGI:MGI:5447616|PMID:16461345
Biological Process	GO:0031175	neuron projection development	Cdk16	IMP		Mouse	MGI:MGI:5050019|PMID:21335063
Biological Process	GO:0031175	neuron projection development	Cdk16	IMP		Mouse	PMID:20534669
Biological Process	GO:0010508	positive regulation of autophagy	CDK16	IDA		Human	PMID:32098961
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	CDK16	IMP		Human	PMID:22798068
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Cdk16	IMP		Mouse	MGI:MGI:5448801|PMID:22798068
Biological Process	GO:0007283	spermatogenesis	Cdk16	IMP		Mouse	MGI:MGI:5319028|PMID:22184064

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern