Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cdk5r1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CDK5R1
- Mouse genes Cdk5r1
- Rat genes Cdk5r1
- Zfish genes cdk5r1a,cdk5r1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk5r1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Cdk5r1	IPI	UniProtKB:P60710	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0051015	actin filament binding	Cdk5r1	IPI	UniProtKB:P60710	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0045296	cadherin binding	Cdk5r1	IDA		Rat	PMID:10753743\|RGD:8554317
Molecular Function	GO:0005509	calcium ion binding	Cdk5r1	IDA		Rat	PMID:12223541\|RGD:8554161
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	Cdk5r1	IMP	MGI:MGI:1931885	Mouse	PMID:11517264
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	Cdk5r1	IDA		Rat	PMID:8662984\|RGD:632374
Molecular Function	GO:0046875	ephrin receptor binding	Cdk5r1	IPI	UniProtKB:D3ZZK3	Rat	PMID:17143272\|RGD:8554385
Molecular Function	GO:0051879	Hsp90 protein binding	Cdk5r1	IPI	UniProtKB:P11499	Mouse	MGI:MGI:6148636\|PMID:17517623
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Cdk5r1	IPI	UniProtKB:Q01097	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0016301	kinase activity	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Molecular Function	GO:0002020	protease binding	Cdk5r1	IPI	UniProtKB:O35350	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q96SN8	Human	PMID:10721722
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:P11798	Human	PMID:12223541
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:12223541
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q7TPR4	Human	PMID:12223541
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:14521924
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q6ZMQ8-1	Human	PMID:14521924
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q6ZMQ8-2	Human	PMID:14521924
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:15689152
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:20133653
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:21220307
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:23543736
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:A2RUH7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:O94983-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:P16422	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:P26715	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:P43356	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:P49184	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q02978	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q6UXH1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q8N2W9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q8NCR3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q96E17	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q96QH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q9BQ29	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q9BT49	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q9HC98-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q9NPC7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q9ULW0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CDK5R1	IPI	UniProtKB:Q00535	Human	PMID:8090221
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:P49615	Mouse	MGI:MGI:5918092\|PMID:17341134
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q8CHT1	Mouse	MGI:MGI:3696283\|PMID:17143272
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:P09803\|UniProtKB:P49615	Mouse	MGI:MGI:5512836\|PMID:18325333
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:P49615	Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q80U04\|UniProtKB:Q8CFH6	Mouse	MGI:MGI:5582660\|PMID:24561619
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:P70424\|UniProtKB:Q61526	Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:O70589	Mouse	PMID:18054859
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:P42227	Mouse	PMID:15096606
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:Q8BR65	Mouse	PMID:15489224
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:P49615	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:Q01097	Mouse	PMID:17529984
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:P49615	Mouse	PMID:12496365
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	PR:P49615	Mouse	PMID:17591690
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q9WU82	Rat	PMID:10753743\|RGD:8554317
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q9Z1Y3	Rat	PMID:10753743\|RGD:8554317
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q03114	Rat	PMID:17036052\|RGD:13432229
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q03114	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:B1WCA1	Rat	PMID:18818692\|RGD:8554573
Molecular Function	GO:0005515	protein binding	Cdk5r1	IPI	UniProtKB:Q03114	Rat	PMID:8846918\|RGD:8554279
Molecular Function	GO:0019901	protein kinase binding	CDK5R1	IPI	UniProtKB:Q8IWU2	Human	PMID:12832520
Molecular Function	GO:0019901	protein kinase binding	Cdk5r1	IPI	UniProtKB:P49615	Mouse	MGI:MGI:3829808\|PMID:19118186
Molecular Function	GO:0019901	protein kinase binding	Cdk5r1	IPI	RGD:70514	Rat	PMID:25665755\|RGD:13782373
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	CDK5R1	IDA		Human	PMID:12832520
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	Cdk5r1	IDA		Rat	PMID:15994305\|RGD:8553752
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	Cdk5r1	IDA		Rat	PMID:8662984\|RGD:632374
Cellular Component	GO:0030424	axon	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0043292	contractile fiber	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	CDK5R1	IPI		Human	PMID:16039528
Cellular Component	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	Cdk5r1	IPI		Mouse	MGI:MGI:5512836\|PMID:18325333
Cellular Component	GO:0005737	cytoplasm	Cdk5r1	IDA		Mouse	PMID:15123626
Cellular Component	GO:0005737	cytoplasm	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0030425	dendrite	Cdk5r1	IDA		Rat	PMID:12223541\|RGD:8554161
Cellular Component	GO:0030425	dendrite	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0043197	dendritic spine	Cdk5r1	IDA		Rat	PMID:12223541\|RGD:8554161
Cellular Component	GO:0030426	growth cone	Cdk5r1	IDA		Rat	PMID:12832520\|RGD:8554468
Cellular Component	GO:0030426	growth cone	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CDK5R1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0016020	membrane	Cdk5r1	IDA		Rat	PMID:17671990\|RGD:13782381
Cellular Component	GO:0031594	neuromuscular junction	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Cellular Component	GO:0043025	neuronal cell body	Cdk5r1	IDA		Rat	PMID:12832520\|RGD:8554468
Cellular Component	GO:0043025	neuronal cell body	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Cellular Component	GO:0005654	nucleoplasm	CDK5R1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Cdk5r1	IDA		Mouse	PMID:15096606
Cellular Component	GO:0005634	nucleus	Cdk5r1	IDA		Mouse	PMID:17591690
Cellular Component	GO:0005634	nucleus	Cdk5r1	IDA		Rat	PMID:16192386\|RGD:8553388
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CDK5R1	IDA		Human	PMID:12832520
Cellular Component	GO:0014069	postsynaptic density	Cdk5r1	IDA		Rat	PMID:17143272\|RGD:8554385
Cellular Component	GO:0098793	presynapse	Cdk5r1	IDA		Rat	PMID:24254883\|RGD:13702178
Cellular Component	GO:0016533	protein kinase 5 complex	CDK5R1	IPI		Human	PMID:15689152
Cellular Component	GO:0016533	protein kinase 5 complex	Cdk5r1	IPI		Mouse	MGI:MGI:5512836\|PMID:18325333
Cellular Component	GO:0016533	protein kinase 5 complex	Cdk5r1	IDA		Rat	PMID:8662984\|RGD:632374
Biological Process	GO:0035881	amacrine cell differentiation	cdk5r1b	IMP	ZFIN:ZDB-MRPHLNO-090106-3	Zfish	PMID:24115595
Biological Process	GO:0007411	axon guidance	Cdk5r1	IMP		Mouse	MGI:MGI:1347398\|PMID:10545161
Biological Process	GO:0007413	axonal fasciculation	Cdk5r1	IMP		Mouse	MGI:MGI:1347398\|PMID:10545161
Biological Process	GO:0007420	brain development	Cdk5r1	IMP		Mouse	MGI:MGI:1347398\|PMID:10545161
Biological Process	GO:0007420	brain development	Cdk5r1	IEP		Rat	PMID:12598607\|RGD:632376
Biological Process	GO:0021549	cerebellum development	Cdk5r1	IMP	MGI:MGI:2680652	Mouse	PMID:11226314
Biological Process	GO:0021549	cerebellum development	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Cdk5r1	IMP		Mouse	MGI:MGI:4821185\|PMID:20624590
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	cdk5r1b	IGI	ZFIN:ZDB-MRPHLNO-090106-2,ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	cdk5r1b	IMP	ZFIN:ZDB-MRPHLNO-090106-2	Zfish	PMID:18753621
Biological Process	GO:0048013	ephrin receptor signaling pathway	Cdk5r1	IMP		Mouse	MGI:MGI:3696283\|PMID:17143272
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	Cdk5r1	IDA		Rat	PMID:11276227\|RGD:8554712
Biological Process	GO:0070315	G1 to G0 transition involved in cell differentiation	Cdk5r1	IMP		Mouse	PMID:21566658
Biological Process	GO:0021766	hippocampus development	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264
Biological Process	GO:0035622	intrahepatic bile duct development	cdk5r1a	IMP	ZFIN:ZDB-GENO-171017-19	Zfish	PMID:28720653
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Cdk5r1	IDA		Rat	PMID:12223541\|RGD:8554161
Biological Process	GO:0021819	layer formation in cerebral cortex	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CDK5R1	IMP		Human	PMID:20357208
Biological Process	GO:0007158	neuron cell-cell adhesion	Cdk5r1	IMP		Mouse	MGI:MGI:3687831\|PMID:10753743
Biological Process	GO:0030182	neuron differentiation	Cdk5r1	IDA		Rat	PMID:8846918\|RGD:8554279
Biological Process	GO:0001764	neuron migration	Cdk5r1	IDA		Mouse	MGI:MGI:86233\|PMID:9010203
Biological Process	GO:0001764	neuron migration	Cdk5r1	IGI	MGI:MGI:108554	Mouse	PMID:11226314
Biological Process	GO:0001764	neuron migration	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264
Biological Process	GO:0001764	neuron migration	Cdk5r1	IGI	MGI:MGI:103022	Mouse	PMID:11226314
Biological Process	GO:0031175	neuron projection development	Cdk5r1	IMP		Rat	PMID:8846918\|RGD:8554279
Biological Process	GO:0018105	peptidyl-serine phosphorylation	CDK5R1	IDA		Human	PMID:12832520
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	CDK5R1	IDA		Human	PMID:12832520
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Cdk5r1	IDA		Rat	PMID:16192386\|RGD:8553388
Biological Process	GO:0045860	positive regulation of protein kinase activity	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Cdk5r1	IDA		Mouse	PMID:18054859
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Cdk5r1	IMP		Mouse	MGI:MGI:4821185\|PMID:20624590
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Cdk5r1	IMP		Mouse	MGI:MGI:3696283\|PMID:17143272
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	Cdk5r1	IMP		Mouse	MGI:MGI:4821185\|PMID:20624590
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Cdk5r1	IDA		Rat	PMID:24254883\|RGD:13702178
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Cdk5r1	IEP		Rat	PMID:24254883\|RGD:13702178
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Cdk5r1	IMP		Rat	PMID:24254883\|RGD:13702178
Biological Process	GO:0060041	retina development in camera-type eye	cdk5r1b	IMP	ZFIN:ZDB-MRPHLNO-090106-3	Zfish	PMID:24115595
Biological Process	GO:0010842	retina layer formation	cdk5r1b	IMP	ZFIN:ZDB-MRPHLNO-090106-2	Zfish	PMID:18753621
Biological Process	GO:0010842	retina layer formation	cdk5r1b	IGI	ZFIN:ZDB-MRPHLNO-090106-2,ZFIN:ZDB-MRPHLNO-090106-4	Zfish	PMID:18753621
Biological Process	GO:0042501	serine phosphorylation of STAT protein	Cdk5r1	IDA		Mouse	PMID:15096606
Biological Process	GO:0021722	superior olivary nucleus maturation	Cdk5r1	IGI	MGI:MGI:1330828	Mouse	PMID:11517264

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.