Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDK8
  • Mouse genes Cdk8
  • Rat genes
  • Zfish genes cdk8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdk8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:Q92585	Human	PMID:15546612
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:Q01094	Human	PMID:18794899
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:19047373
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:19914168
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:20098423
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:21806996
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:23746844
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:25344755
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:26502155
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDK8	IPI	UniProtKB:P24863	Human	PMID:7568034
Molecular Function	GO:0005515	protein binding	Cdk8	IPI	UniProtKB:A2AGH6	Mouse	MGI:MGI:5615331|PMID:25344755
Molecular Function	GO:0005515	protein binding	Cdk8	IPI	UniProtKB:A2AGH6	Mouse	MGI:MGI:4833901|PMID:20720539
Molecular Function	GO:0004672	protein kinase activity	CDK8	IMP		Human	PMID:30905399
Cellular Component	GO:0016592	mediator complex	CDK8	IDA		Human	PMID:14638676
Cellular Component	GO:0016592	mediator complex	CDK8	IMP		Human	PMID:30905399
Cellular Component	GO:0016592	mediator complex	Cdk8	IDA		Mouse	PMID:15340084
Cellular Component	GO:0005730	nucleolus	CDK8	IDA		Human	PMID:22869755
Cellular Component	GO:0005634	nucleus	CDK8	IDA		Human	PMID:16109376
Cellular Component	GO:0032991	protein-containing complex	CDK8	IDA		Human	PMID:22869755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern