Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDKN1C
  • Mouse genes Cdkn1c
  • Rat genes Cdkn1c
  • Zfish genes cdkn1ca,cdkn1cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdkn1c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140678	molecular function inhibitor activity	CDKN1C	IMP		Human	PMID:11746698
Molecular Function	GO:0005515	protein binding	CDKN1C	IPI	UniProtKB:P33993	Human	PMID:16289477
Molecular Function	GO:0005515	protein binding	CDKN1C	IPI	UniProtKB:Q9NXK8	Human	PMID:18660753
Molecular Function	GO:0005515	protein binding	CDKN1C	IPI	UniProtKB:Q14207	Human	PMID:19170105
Molecular Function	GO:0005515	protein binding	CDKN1C	IPI	UniProtKB:P12004	Human	PMID:22634751
Molecular Function	GO:0005515	protein binding	Cdkn1c	IPI	PR:Q06219	Mouse	PMID:14671317
Molecular Function	GO:0005515	protein binding	Cdkn1c	IPI	RGD:1562456	Rat	PMID:19533683|RGD:2315050
Molecular Function	GO:0004860	protein kinase inhibitor activity	CDKN1C	IMP		Human	PMID:11746698
Molecular Function	GO:0044877	protein-containing complex binding	CDKN1C	IPI	ComplexPortal:CPX-2006	Human	PMID:11746698
Cellular Component	GO:0005737	cytoplasm	CDKN1C	IDA		Human	PMID:16943770
Cellular Component	GO:0005634	nucleus	CDKN1C	IDA		Human	PMID:16943770
Cellular Component	GO:0005634	nucleus	Cdkn1c	IDA		Mouse	PMID:11737597
Cellular Component	GO:0005634	nucleus	Cdkn1c	IDA		Mouse	PMID:19228596
Biological Process	GO:0030325	adrenal gland development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0030325	adrenal gland development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0043010	camera-type eye development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0043010	camera-type eye development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0001708	cell fate specification	cdkn1ca	IMP	ZFIN:ZDB-MRPHLNO-050831-1	Zfish	PMID:16033893
Biological Process	GO:0055123	digestive system development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0055123	digestive system development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0060669	embryonic placenta morphogenesis	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0060669	embryonic placenta morphogenesis	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0071514	genomic imprinting	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0071514	genomic imprinting	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0010001	glial cell differentiation	cdkn1ca	IMP	ZFIN:ZDB-MRPHLNO-050831-1	Zfish	PMID:16033893
Biological Process	GO:0001822	kidney development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0001822	kidney development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0035264	multicellular organism growth	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0035264	multicellular organism growth	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0030099	myeloid cell differentiation	Cdkn1c	IGI	MGI:MGI:2143628	Mouse	PMID:15889154
Biological Process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	CDKN1C	IMP		Human	PMID:11746698
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CDKN1C	IDA		Human	PMID:19170105
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	CDKN1C	IMP		Human	PMID:16943770
Biological Process	GO:0033673	negative regulation of kinase activity	CDKN1C	IDA		Human	PMID:19170105
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	cdkn1ca	IMP	ZFIN:ZDB-MRPHLNO-050908-1	Zfish	PMID:15891769
Biological Process	GO:0042326	negative regulation of phosphorylation	CDKN1C	IDA		Human	PMID:19170105
Biological Process	GO:0042326	negative regulation of phosphorylation	Cdkn1c	IDA		Mouse	MGI:MGI:3852291|PMID:19170105
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cdkn1c	IGI	MGI:MGI:1352456	Mouse	PMID:14671317
Biological Process	GO:0042551	neuron maturation	Cdkn1c	IMP	MGI:MGI:1933757	Mouse	PMID:14671317
Biological Process	GO:0001890	placenta development	Cdkn1c	IGI	MGI:MGI:104565	Mouse	PMID:9784491
Biological Process	GO:0001890	placenta development	Cdkn1c	IMP		Mouse	PMID:21729874
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CDKN1C	IGI	UniProtKB:Q9BQA5	Human	PMID:19170105
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	CDKN1C	IMP		Human	PMID:16943770
Biological Process	GO:0007096	regulation of exit from mitosis	Cdkn1c	IGI	MGI:MGI:104565	Mouse	PMID:9784491
Biological Process	GO:1902746	regulation of lens fiber cell differentiation	Cdkn1c	IGI	MGI:MGI:104565	Mouse	PMID:9784491
Biological Process	GO:0001501	skeletal system development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0001501	skeletal system development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117
Biological Process	GO:0060065	uterus development	Cdkn1c	IMP	MGI:MGI:3840687	Mouse	PMID:19276117
Biological Process	GO:0060065	uterus development	Cdkn1c	IMP	MGI:MGI:1933758	Mouse	PMID:19276117

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern