Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDKN2D
  • Mouse genes Cdkn2d
  • Rat genes
  • Zfish genes cdkn2d
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdkn2d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	CDKN2D	IDA		Human	PMID:8741839
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6P1W5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9UKT9	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:F1D8N6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P22736	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q0VD86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6P1W5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9BPX1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9UKT9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q13363-2	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9BPX1	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P22736	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P43354	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q0VD86	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6P1W5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9UKT9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:A0A0C4DGF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:A4QMS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:A8MW99	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:O00746	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:O95678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P0C7X2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P17568	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P30044	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P30281	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P43354	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q04637-9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q17RB8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q3SY00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q49A26-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q4VC12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6NX45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6ZNE9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q86W67	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q8IYX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q8WW35	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q8WXI9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q92570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q96LW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q96N95-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q99990	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9BPX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9BRT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9NVL1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9NVV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9UFW8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q9Y483-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:9751050
Molecular Function	GO:0019901	protein kinase binding	CDKN2D	IPI	UniProtKB:P11802	Human	PMID:8741839
Molecular Function	GO:0019901	protein kinase binding	CDKN2D	IPI	UniProtKB:Q00534	Human	PMID:8741839
Molecular Function	GO:0019901	protein kinase binding	Cdkn2d	IPI	PR:Q64261	Mouse	PMID:7739547
Molecular Function	GO:0019901	protein kinase binding	Cdkn2d	IPI	PR:P30285	Mouse	PMID:7739547
Cellular Component	GO:0097129	cyclin D2-CDK4 complex	Cdkn2d	IDA		Mouse	PMID:7739547
Cellular Component	GO:0005737	cytoplasm	CDKN2D	IDA		Human	PMID:15750620
Cellular Component	GO:0005829	cytosol	CDKN2D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CDKN2D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CDKN2D	IDA		Human	PMID:15750620
Cellular Component	GO:0005634	nucleus	CDKN2D	IDA		Human	PMID:8741839
Biological Process	GO:0048102	autophagic cell death	CDKN2D	IMP		Human	PMID:16322758
Biological Process	GO:0000731	DNA synthesis involved in DNA repair	CDKN2D	IMP		Human	PMID:15750620
Biological Process	GO:1902807	negative regulation of cell cycle G1/S phase transition	Cdkn2d	IDA		Mouse	PMID:7739547
Biological Process	GO:0030308	negative regulation of cell growth	CDKN2D	IDA		Human	PMID:10208428
Biological Process	GO:0008285	negative regulation of cell population proliferation	CDKN2D	IDA		Human	PMID:10208428
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	CDKN2D	IMP		Human	PMID:15750620
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	CDKN2D	IMP		Human	PMID:15750620
Biological Process	GO:0042326	negative regulation of phosphorylation	CDKN2D	IDA		Human	PMID:10208428
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	CDKN2D	IDA		Human	PMID:8741839
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	CDKN2D	IDA		Human	PMID:10208428
Biological Process	GO:0032526	response to retinoic acid	CDKN2D	IMP		Human	PMID:16322758
Biological Process	GO:0009411	response to UV	CDKN2D	IMP		Human	PMID:15750620
Biological Process	GO:0033280	response to vitamin D	CDKN2D	IMP		Human	PMID:16322758
Biological Process	GO:0007605	sensory perception of sound	Cdkn2d	IMP	MGI:MGI:1927668	Mouse	PMID:12717441

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern