Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CDX4
  • Mouse genes Cdx4
  • Rat genes Cdx4
  • Zfish genes cdx4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cdx4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	cdx4	IDA		Zfish	PMID:24286030
Molecular Function	GO:0003677	DNA binding	cdx4	IDA		Zfish	PMID:13679919
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CDX4	IDA		Human	PMID:21471217
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CDX4	IMP		Human	PMID:21471217
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:O43741	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:P25791	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:P25800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:P61024	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:Q13131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:O43741	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CDX4	IPI	UniProtKB:P54646	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CDX4	IDA		Human	PMID:21471217
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CDX4	IDA		Human	PMID:28473536
Biological Process	GO:0009948	anterior/posterior axis specification	cdx4	IGI	ZFIN:ZDB-GENE-000329-2,ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0009948	anterior/posterior axis specification	cdx4	IGI	ZFIN:ZDB-GENE-000823-1,ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0009952	anterior/posterior pattern specification	Cdx4	IGI	MGI:MGI:88361	Mouse	PMID:19853565
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx4	IMP	ZFIN:ZDB-GENO-080715-2	Zfish	PMID:18234725
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx4	IMP	ZFIN:ZDB-MRPHLNO-050509-7	Zfish	PMID:18234725
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx4	IGI	ZFIN:ZDB-GENO-080715-2,ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:18234725
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx4	IMP	ZFIN:ZDB-GENO-980202-1126	Zfish	PMID:17823612
Biological Process	GO:0009952	anterior/posterior pattern specification	cdx4	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0001568	blood vessel development	Cdx4	IGI	MGI:MGI:88361	Mouse	PMID:16396910
Biological Process	GO:0048617	embryonic foregut morphogenesis	cdx4	IMP	ZFIN:ZDB-GENO-080715-2	Zfish	PMID:18234725
Biological Process	GO:0030097	hemopoiesis	cdx4	IGI	ZFIN:ZDB-GENO-980202-1126,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:16457800
Biological Process	GO:0021906	hindbrain-spinal cord boundary formation	cdx4	IMP	ZFIN:ZDB-MRPHLNO-050509-7	Zfish	PMID:17507415
Biological Process	GO:0060711	labyrinthine layer development	Cdx4	IGI	MGI:MGI:88361	Mouse	PMID:19853565
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cdx4	IGI	MGI:MGI:101893	Mouse	PMID:16325584
Biological Process	GO:0031016	pancreas development	cdx4	IMP	ZFIN:ZDB-GENO-080715-1	Zfish	PMID:18234725
Biological Process	GO:0031016	pancreas development	cdx4	IMP	ZFIN:ZDB-GENO-080715-2	Zfish	PMID:18234725
Biological Process	GO:0031016	pancreas development	cdx4	IGI	ZFIN:ZDB-GENO-080715-2,ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:18234725
Biological Process	GO:0003311	pancreatic D cell differentiation	cdx4	IMP	ZFIN:ZDB-GENO-980202-1126	Zfish	PMID:28327131
Biological Process	GO:0001890	placenta development	Cdx4	IGI	MGI:MGI:88361	Mouse	PMID:16396910
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDX4	IDA		Human	PMID:21471217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CDX4	IMP		Human	PMID:21471217
Biological Process	GO:0036342	post-anal tail morphogenesis	cdx4	IMP	ZFIN:ZDB-GENO-980202-947	Zfish	PMID:9007236
Biological Process	GO:0048793	pronephros development	cdx4	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0048793	pronephros development	cdx4	IMP	ZFIN:ZDB-GENO-080215-1	Zfish	PMID:17953490
Biological Process	GO:0010468	regulation of gene expression	cdx4	IMP	ZFIN:ZDB-GENO-080715-2	Zfish	PMID:26335559
Biological Process	GO:0010468	regulation of gene expression	cdx4	IMP	ZFIN:ZDB-GENO-980202-1126	Zfish	PMID:26335559
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	cdx4	IGI	ZFIN:ZDB-GENO-080215-1,ZFIN:ZDB-MRPHLNO-060602-1	Zfish	PMID:17953490
Biological Process	GO:0021903	rostrocaudal neural tube patterning	cdx4	IGI	ZFIN:ZDB-MRPHLNO-050509-3,ZFIN:ZDB-MRPHLNO-050509-7	Zfish	PMID:17079270
Biological Process	GO:0001756	somitogenesis	cdx4	IGI	ZFIN:ZDB-MRPHLNO-050509-3	Zfish	PMID:15708563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern