Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CELSR1
  • Mouse genes Celsr1
  • Rat genes Celsr1
  • Zfish genes celsr1a,celsr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Celsr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Celsr1	IPI	UniProtKB:Q7T0S3	Mouse	MGI:MGI:5512932|PMID:23292348
Molecular Function	GO:0005515	protein binding	Celsr1	IPI	PR:Q91ZD4	Mouse	PMID:18849982
Cellular Component	GO:0016020	membrane	Celsr1	IDA		Mouse	PMID:20353824
Cellular Component	GO:0005654	nucleoplasm	CELSR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CELSR1	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Celsr1	IMP	MGI:MGI:4430218	Mouse	PMID:19357712
Biological Process	GO:0009952	anterior/posterior pattern specification	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:18849982
Biological Process	GO:0045176	apical protein localization	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:16687519
Biological Process	GO:0042074	cell migration involved in gastrulation	celsr1a	IMP	ZFIN:ZDB-MRPHLNO-050823-1	Zfish	PMID:15882862
Biological Process	GO:0042074	cell migration involved in gastrulation	celsr1a	IGI	ZFIN:ZDB-MRPHLNO-050823-1,ZFIN:ZDB-MRPHLNO-050823-4	Zfish	PMID:15882862
Biological Process	GO:0042074	cell migration involved in gastrulation	celsr1b	IMP	ZFIN:ZDB-MRPHLNO-050823-4	Zfish	PMID:15882862
Biological Process	GO:0042074	cell migration involved in gastrulation	celsr1b	IGI	ZFIN:ZDB-MRPHLNO-050823-1,ZFIN:ZDB-MRPHLNO-050823-4	Zfish	PMID:15882862
Biological Process	GO:0048105	establishment of body hair planar orientation	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:18849982
Biological Process	GO:0048105	establishment of body hair planar orientation	Celsr1	IMP	MGI:MGI:4430218	Mouse	PMID:19357712
Biological Process	GO:0001736	establishment of planar polarity	Celsr1	IMP		Mouse	MGI:MGI:2667273|PMID:12842012
Biological Process	GO:0042249	establishment of planar polarity of embryonic epithelium	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:12842012
Biological Process	GO:0042249	establishment of planar polarity of embryonic epithelium	Celsr1	IMP	MGI:MGI:1862019	Mouse	PMID:12842012
Biological Process	GO:0001942	hair follicle development	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:18849982
Biological Process	GO:0007507	heart development	celsr1a	IGI	ZFIN:ZDB-MRPHLNO-200121-1,ZFIN:ZDB-MRPHLNO-200121-2	Zfish	PMID:27756857
Biological Process	GO:0007507	heart development	celsr1b	IGI	ZFIN:ZDB-MRPHLNO-200121-1,ZFIN:ZDB-MRPHLNO-200121-2	Zfish	PMID:27756857
Biological Process	GO:0042472	inner ear morphogenesis	Celsr1	IMP	MGI:MGI:1862019	Mouse	PMID:12842012
Biological Process	GO:0042472	inner ear morphogenesis	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:12842012
Biological Process	GO:0060490	lateral sprouting involved in lung morphogenesis	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20223754
Biological Process	GO:0007626	locomotory behavior	Celsr1	IMP	MGI:MGI:1862019	Mouse	PMID:10932191
Biological Process	GO:0097475	motor neuron migration	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20631168
Biological Process	GO:0001843	neural tube closure	Celsr1	IMP		Mouse	MGI:MGI:2667273|PMID:12842012
Biological Process	GO:0001843	neural tube closure	Celsr1	IGI	MGI:MGI:107926	Mouse	PMID:17229766
Biological Process	GO:0001843	neural tube closure	Celsr1	IGI	MGI:MGI:2135272	Mouse	PMID:17229766
Biological Process	GO:0021915	neural tube development	celsr1a	IGI	ZFIN:ZDB-MRPHLNO-200121-1,ZFIN:ZDB-MRPHLNO-200121-2	Zfish	PMID:27756857
Biological Process	GO:0021915	neural tube development	celsr1b	IGI	ZFIN:ZDB-MRPHLNO-200121-1,ZFIN:ZDB-MRPHLNO-200121-2	Zfish	PMID:27756857
Biological Process	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20223754
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	Celsr1	IGI	MGI:MGI:1918711	Mouse	PMID:20704721
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	Celsr1	IGI	MGI:MGI:2135272	Mouse	PMID:20704721
Biological Process	GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20223754
Biological Process	GO:0090251	protein localization involved in establishment of planar polarity	Celsr1	IDA		Mouse	PMID:18849982
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20223754
Biological Process	GO:0007266	Rho protein signal transduction	Celsr1	IMP	MGI:MGI:2668337	Mouse	PMID:20223754
Biological Process	GO:0019827	stem cell population maintenance	celsr1a	IMP	ZFIN:ZDB-GENO-220714-7	Zfish	PMID:31985398
Biological Process	GO:0001894	tissue homeostasis	celsr1a	IMP	ZFIN:ZDB-GENO-220714-7	Zfish	PMID:31985398
Biological Process	GO:0042060	wound healing	Celsr1	IGI	MGI:MGI:2135272	Mouse	PMID:20643356
Biological Process	GO:0042060	wound healing	Celsr1	IGI	MGI:MGI:2655333	Mouse	PMID:20643356
Biological Process	GO:0042060	wound healing	Celsr1	IGI	MGI:MGI:1918711	Mouse	PMID:20643356
Biological Process	GO:0042060	wound healing	Celsr1	IGI	MGI:MGI:2145950	Mouse	PMID:20643356

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern