Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CEMIP2
  • Mouse genes Cemip2
  • Rat genes Cemip2
  • Zfish genes cemip2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cemip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	CEMIP2	HDA		Human	PMID:25468996
Molecular Function	GO:0005509	calcium ion binding	CEMIP2	IDA		Human	PMID:28246172
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	CEMIP2	IDA		Human	PMID:28246172
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	cemip2	IMP		Zfish	PMID:31444829
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	cemip2	IDA		Zfish	PMID:28118600
Cellular Component	GO:0005829	cytosol	CEMIP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CEMIP2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CEMIP2	HDA		Human	PMID:20458337
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CEMIP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	CEMIP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CEMIP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CEMIP2	IDA		Human	PMID:28246172
Biological Process	GO:0003190	atrioventricular valve formation	cemip2	IMP		Zfish	PMID:21896630|ZFIN:ZDB-PUB-110914-2
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	cemip2	IMP	ZFIN:ZDB-GENO-161101-5	Zfish	PMID:27471259
Biological Process	GO:0060974	cell migration involved in heart formation	cemip2	IMP	ZFIN:ZDB-GENO-120216-2	Zfish	PMID:21896630
Biological Process	GO:0003318	cell migration to the midline involved in heart development	cemip2	IMP		Zfish	PMID:21896630|ZFIN:ZDB-PUB-110914-2
Biological Process	GO:0003143	embryonic heart tube morphogenesis	cemip2	IMP	ZFIN:ZDB-GENO-110802-6	Zfish	PMID:21896629
Biological Process	GO:0003143	embryonic heart tube morphogenesis	cemip2	IMP	ZFIN:ZDB-GENO-120216-2	Zfish	PMID:21896630
Biological Process	GO:0003143	embryonic heart tube morphogenesis	cemip2	IMP	ZFIN:ZDB-GENO-110802-7	Zfish	PMID:21896629
Biological Process	GO:0003143	embryonic heart tube morphogenesis	cemip2	IMP	ZFIN:ZDB-MRPHLNO-110923-2	Zfish	PMID:21896629
Biological Process	GO:0003197	endocardial cushion development	cemip2	IMP	ZFIN:ZDB-GENO-110802-7	Zfish	PMID:21896629
Biological Process	GO:0003197	endocardial cushion development	cemip2	IMP	ZFIN:ZDB-GENO-110802-6	Zfish	PMID:21896629
Biological Process	GO:0001947	heart looping	cemip2	IMP		Zfish	PMID:21896629|ZFIN:ZDB-PUB-110914-5
Biological Process	GO:0030214	hyaluronan catabolic process	CEMIP2	IDA		Human	PMID:28246172
Biological Process	GO:0030214	hyaluronan catabolic process	cemip2	IDA		Zfish	PMID:28118600|ZFIN:ZDB-PUB-170125-2
Biological Process	GO:0030214	hyaluronan catabolic process	cemip2	IMP	ZFIN:ZDB-GENO-170627-5	Zfish	PMID:28118600
Biological Process	GO:0016203	muscle attachment	cemip2	IMP	ZFIN:ZDB-GENO-161101-5	Zfish	PMID:27471259
Biological Process	GO:0060415	muscle tissue morphogenesis	cemip2	IMP	ZFIN:ZDB-GENO-161101-5	Zfish	PMID:27471259
Biological Process	GO:1901203	positive regulation of extracellular matrix assembly	cemip2	IMP	ZFIN:ZDB-GENO-161101-5	Zfish	PMID:27471259
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	cemip2	IDA		Zfish	PMID:28118600|ZFIN:ZDB-PUB-170125-2
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	cemip2	IMP	ZFIN:ZDB-GENO-170627-5	Zfish	PMID:28118600
Biological Process	GO:1903670	regulation of sprouting angiogenesis	cemip2	IMP		Zfish	PMID:28118600|ZFIN:ZDB-PUB-170125-2
Biological Process	GO:1903670	regulation of sprouting angiogenesis	cemip2	IMP	ZFIN:ZDB-GENO-170627-5	Zfish	PMID:28118600
Biological Process	GO:0030111	regulation of Wnt signaling pathway	cemip2	IMP	ZFIN:ZDB-GENO-120216-1	Zfish	PMID:31444829

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern