Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CENPA
  • Mouse genes Cenpa
  • Rat genes Cenpa
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cenpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:P62805	Human	PMID:19410544
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q8NCD3	Human	PMID:19410544
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:P06748	Human	PMID:19410545
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q8NCD3	Human	PMID:19410545
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q03188	Human	PMID:19503796
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q5EE01	Human	PMID:19533040
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q8NCD3-1	Human	PMID:20080577
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:P62805	Human	PMID:21478274
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q8NCD3	Human	PMID:21478274
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:P49736	Human	PMID:26167883
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:P62805	Human	PMID:26167883
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q8NCD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CENPA	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Cellular Component	GO:0061638	CENP-A containing chromatin	Cenpa	IDA		Mouse	PMID:14519686
Cellular Component	GO:0043505	CENP-A containing nucleosome	CENPA	IPI		Human	PMID:21743476
Cellular Component	GO:0043505	CENP-A containing nucleosome	CENPA	IDA		Human	PMID:18195732
Cellular Component	GO:0000775	chromosome, centromeric region	CENPA	IDA		Human	PMID:11084331
Cellular Component	GO:0000775	chromosome, centromeric region	CENPA	IDA		Human	PMID:27499292
Cellular Component	GO:0000775	chromosome, centromeric region	Cenpa	IDA		Mouse	PMID:22516971
Cellular Component	GO:0000779	condensed chromosome, centromeric region	CENPA	IDA		Human	PMID:11682612
Cellular Component	GO:0000779	condensed chromosome, centromeric region	Cenpa	IDA		Mouse	PMID:15242786
Cellular Component	GO:0005654	nucleoplasm	CENPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	CENPA	IDA		Human	PMID:27499292
Cellular Component	GO:0005634	nucleus	CENPA	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	CENPA	IDA		Human	PMID:27499292
Cellular Component	GO:0005721	pericentric heterochromatin	Cenpa	IDA		Mouse	PMID:15242786
Biological Process	GO:0034080	CENP-A containing chromatin assembly	CENPA	IDA		Human	PMID:11682612
Biological Process	GO:0000132	establishment of mitotic spindle orientation	CENPA	IMP		Human	PMID:19468067
Biological Process	GO:0051382	kinetochore assembly	CENPA	IDA		Human	PMID:11682612
Biological Process	GO:0000281	mitotic cytokinesis	CENPA	IMP		Human	PMID:27499292
Biological Process	GO:0071459	protein localization to chromosome, centromeric region	CENPA	IDA		Human	PMID:11682612

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern