Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CENPC
  • Mouse genes Cenpc1
  • Rat genes Cenpc
  • Zfish genes si:ch211-161h7.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cenpc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CENPC	IPI	UniProtKB:Q03188	Human	PMID:19503796
Molecular Function	GO:0005515	protein binding	CENPC	IPI	UniProtKB:P49450	Human	PMID:19503796
Molecular Function	GO:0005515	protein binding	Cenpc1	IPI	UniProtKB:O08586	Mouse	MGI:MGI:3706446|PMID:17218262
Molecular Function	GO:0005515	protein binding	Cenpc1	IPI	PR:Q5F2C3	Mouse	PMID:25533956
Cellular Component	GO:0000779	condensed chromosome, centromeric region	CENPC	IDA		Human	PMID:11682612
Cellular Component	GO:0000779	condensed chromosome, centromeric region	Cenpc1	IDA		Mouse	PMID:15242786
Cellular Component	GO:0000776	kinetochore	CENPC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	CENPC	IDA		Human	PMID:21529714
Cellular Component	GO:0030496	midbody	CENPC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	CENPC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CENPC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005721	pericentric heterochromatin	CENPC	IDA		Human	PMID:21529714
Cellular Component	GO:0005721	pericentric heterochromatin	Cenpc1	IDA		Mouse	PMID:15242786
Biological Process	GO:0007059	chromosome segregation	CENPC	IMP		Human	PMID:21529714
Biological Process	GO:0051382	kinetochore assembly	CENPC	IMP		Human	PMID:21529714
Biological Process	GO:0000278	mitotic cell cycle	CENPC	IMP		Human	PMID:21529714

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern