Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CEP250
  • Mouse genes Cep250
  • Rat genes Cep250
  • Zfish genes si:dkey-230p4.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cep250

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:P51955	Human	PMID:10880350
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:Q66GS9	Human	PMID:18851962
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:O88566	Human	PMID:20300119
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:Q9H0K1	Human	PMID:20708153
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:Q68D86	Human	PMID:30404835
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CEP250	IPI	UniProtKB:P51955	Human	PMID:9647649
Molecular Function	GO:0019904	protein domain specific binding	CEP250	IPI	UniProtKB:Q9NXG0	Human	PMID:24554434
Cellular Component	GO:0005814	centriole	CEP250	IDA		Human	PMID:11076968
Cellular Component	GO:0005814	centriole	CEP250	IDA		Human	PMID:18851962
Cellular Component	GO:0005814	centriole	CEP250	IDA		Human	PMID:24421332
Cellular Component	GO:0005814	centriole	CEP250	IDA		Human	PMID:26337392
Cellular Component	GO:0005814	centriole	CEP250	IDA		Human	PMID:27623382
Cellular Component	GO:0005814	centriole	Cep250	IDA		Mouse	PMID:15784680
Cellular Component	GO:0005814	centriole	Cep250	IDA		Mouse	PMID:19117032
Cellular Component	GO:0005813	centrosome	CEP250	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	CEP250	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	CEP250	IDA		Human	PMID:31974111
Cellular Component	GO:0005813	centrosome	CEP250	IDA		Human	PMID:9647649
Cellular Component	GO:0036064	ciliary basal body	Cep250	IDA		Mouse	MGI:MGI:6317055|PMID:30998843
Cellular Component	GO:0070062	extracellular exosome	CEP250	HDA		Human	PMID:19056867
Cellular Component	GO:0001917	photoreceptor inner segment	Cep250	IDA		Mouse	MGI:MGI:6317055|PMID:30998843
Cellular Component	GO:0001750	photoreceptor outer segment	Cep250	IDA		Mouse	MGI:MGI:6254746|PMID:28005958
Cellular Component	GO:0032991	protein-containing complex	CEP250	IMP		Human	PMID:10880350
Cellular Component	GO:0031616	spindle pole centrosome	Cep250	IDA		Mouse	PMID:19117032
Biological Process	GO:0010457	centriole-centriole cohesion	CEP250	IMP		Human	PMID:11076968
Biological Process	GO:0010457	centriole-centriole cohesion	CEP250	IMP		Human	PMID:18851962
Biological Process	GO:0010457	centriole-centriole cohesion	CEP250	IMP		Human	PMID:23213374
Biological Process	GO:0010457	centriole-centriole cohesion	CEP250	IMP		Human	PMID:24554434
Biological Process	GO:0060271	cilium assembly	CEP250	IMP		Human	PMID:28005958
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Cep250	IMP		Mouse	MGI:MGI:6317055|PMID:30998843
Biological Process	GO:0000278	mitotic cell cycle	CEP250	IDA		Human	PMID:12140259
Biological Process	GO:1905515	non-motile cilium assembly	CEP250	IMP		Human	PMID:23789104
Biological Process	GO:1904781	positive regulation of protein localization to centrosome	CEP250	IMP		Human	PMID:27623382
Biological Process	GO:0008104	protein localization	CEP250	IMP		Human	PMID:18851962
Biological Process	GO:0008104	protein localization	CEP250	IMP		Human	PMID:23213374
Biological Process	GO:0071539	protein localization to centrosome	CEP250	IMP		Human	PMID:30404835
Biological Process	GO:0033365	protein localization to organelle	CEP250	IMP		Human	PMID:24554434
Biological Process	GO:0030997	regulation of centriole-centriole cohesion	CEP250	IDA		Human	PMID:9647649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern