Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CERS1
  • Mouse genes Cers1
  • Rat genes Cers1
  • Zfish genes cers1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cers1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016410	N-acyltransferase activity	Cers1	IMP		Mouse	MGI:MGI:5008665|PMID:21625621
Molecular Function	GO:0005515	protein binding	Cers1	IPI	UniProtKB:Q8R104	Mouse	MGI:MGI:5755322|PMID:26620563
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	CERS1	IDA		Human	PMID:24782409
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	Cers1	IDA		Mouse	MGI:MGI:3764760|PMID:17977534
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	Cers1	IDA		Mouse	MGI:MGI:3696321|PMID:16951403
Cellular Component	GO:0005783	endoplasmic reticulum	CERS1	IDA		Human	PMID:17699106
Cellular Component	GO:0005783	endoplasmic reticulum	CERS1	IDA		Human	PMID:19800881
Cellular Component	GO:0005783	endoplasmic reticulum	CERS1	IDA		Human	PMID:24782409
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cers1	IDA		Mouse	MGI:MGI:3696321|PMID:16951403
Biological Process	GO:0007420	brain development	Cers1	IMP	MGI:MGI:2653507	Mouse	PMID:15248193
Biological Process	GO:0072721	cellular response to dithiothreitol	CERS1	IDA		Human	PMID:19800881
Biological Process	GO:0036146	cellular response to mycotoxin	CERS1	IDA		Human	PMID:12105227
Biological Process	GO:0071492	cellular response to UV-A	CERS1	IDA		Human	PMID:19800881
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	CERS1	IDA		Human	PMID:19800881
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:12105227
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:12869556
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:15823095
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:17548428
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:18541923
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:22922758
Biological Process	GO:0046513	ceramide biosynthetic process	CERS1	IDA		Human	PMID:24782409
Biological Process	GO:0046513	ceramide biosynthetic process	Cers1	IDA		Mouse	MGI:MGI:3764760|PMID:17977534
Biological Process	GO:0046513	ceramide biosynthetic process	Cers1	IMP		Mouse	MGI:MGI:5008665|PMID:21625621
Biological Process	GO:0046513	ceramide biosynthetic process	Cers1	IDA		Mouse	MGI:MGI:5755322|PMID:26620563
Biological Process	GO:0046513	ceramide biosynthetic process	Cers1	IDA		Mouse	MGI:MGI:3696321|PMID:16951403
Biological Process	GO:0046513	ceramide biosynthetic process	Cers1	IMP		Mouse	MGI:MGI:6380950|PMID:30605666
Biological Process	GO:0046325	negative regulation of glucose import	Cers1	IMP		Mouse	MGI:MGI:6380950|PMID:30605666
Biological Process	GO:0051974	negative regulation of telomerase activity	CERS1	IDA		Human	PMID:17548428
Biological Process	GO:1901526	positive regulation of mitophagy	CERS1	IDA		Human	PMID:22922758
Biological Process	GO:0030148	sphingolipid biosynthetic process	CERS1	IDA		Human	PMID:12105227

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern