Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CERS6
  • Mouse genes Cers6
  • Rat genes Cers6
  • Zfish genes cers6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cers6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CERS6	IPI	UniProtKB:P30556	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	CERS6	IPI	UniProtKB:P41146	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	Cers6	IPI	UniProtKB:Q8R104	Mouse	MGI:MGI:5755322|PMID:26620563
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	CERS6	IDA		Human	PMID:17609214
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	CERS6	IDA		Human	PMID:17977534
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	Cers6	IMP		Mouse	MGI:MGI:5513027|PMID:23760501
Molecular Function	GO:0050291	sphingosine N-acyltransferase activity	Cers6	IDA		Mouse	PMID:15823095
Cellular Component	GO:0005783	endoplasmic reticulum	Cers6	IDA		Mouse	PMID:15823095
Cellular Component	GO:0016020	membrane	CERS6	HDA		Human	PMID:19946888
Biological Process	GO:0046513	ceramide biosynthetic process	CERS6	IDA		Human	PMID:17609214
Biological Process	GO:0046513	ceramide biosynthetic process	CERS6	IDA		Human	PMID:17977534
Biological Process	GO:0046513	ceramide biosynthetic process	Cers6	IMP		Mouse	MGI:MGI:5513027|PMID:23760501
Biological Process	GO:0046513	ceramide biosynthetic process	Cers6	IDA		Mouse	MGI:MGI:5755322|PMID:26620563
Biological Process	GO:0046513	ceramide biosynthetic process	Cers6	IDA		Mouse	PMID:15823095
Biological Process	GO:0014003	oligodendrocyte development	Cers6	IEP		Rat	PMID:21148554|RGD:156431059
Biological Process	GO:1900143	positive regulation of oligodendrocyte apoptotic process	Cers6	IMP		Rat	PMID:21148554|RGD:156431059
Biological Process	GO:0030148	sphingolipid biosynthetic process	Cers6	IDA		Mouse	PMID:15823095

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern