Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CERT1
  • Mouse genes Cert1
  • Rat genes Cert1
  • Zfish genes cert1a,cert1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cert1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097001	ceramide binding	CERT1	IDA		Human	PMID:18184806
Molecular Function	GO:0120017	ceramide transfer activity	CERT1	IDA		Human	PMID:18184806
Molecular Function	GO:0016301	kinase activity	Cert1	IDA		Mouse	PMID:11007769
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q01955	Human	PMID:10212244
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:O95197	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:P78368	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q13352	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q9NQC3	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q9P0L0	Human	PMID:16895911
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:P78368	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q13352	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q15041	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q9H568	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q8NHP6	Human	PMID:29858488
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:O95197	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q15041	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q9NQC3	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:O95197	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q15041	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:Q9NQC3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CERT1	IPI	UniProtKB:P78368	Human	PMID:32707033
Cellular Component	GO:0005829	cytosol	Cert1	IDA		Mouse	PMID:19139267
Cellular Component	GO:0005794	Golgi apparatus	CERT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	CERT1	IDA		Human	PMID:18184806
Cellular Component	GO:0005794	Golgi apparatus	CERT1	IDA		Human	PMID:29858488
Cellular Component	GO:0005739	mitochondrion	Cert1	IDA		Mouse	PMID:19139267
Cellular Component	GO:0005654	nucleoplasm	CERT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CERT1	IDA		Human	PMID:16895911
Biological Process	GO:0000902	cell morphogenesis	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0008283	cell population proliferation	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0006672	ceramide metabolic process	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0007029	endoplasmic reticulum organization	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0035621	ER to Golgi ceramide transport	CERT1	IMP		Human	PMID:18184806
Biological Process	GO:0035621	ER to Golgi ceramide transport	Cert1	IMP	MGI:3837565	Mouse	PMID:24642596
Biological Process	GO:0003007	heart morphogenesis	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0001701	in utero embryonic development	Cert1	IMP	MGI:MGI:5287775	Mouse	PMID:27996060
Biological Process	GO:0001701	in utero embryonic development	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0120012	intermembrane sphingolipid transfer	CERT1	IDA		Human	PMID:18184806
Biological Process	GO:0055088	lipid homeostasis	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0070584	mitochondrion morphogenesis	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0006936	muscle contraction	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267
Biological Process	GO:0007165	signal transduction	Cert1	IMP	MGI:MGI:3837565	Mouse	PMID:19139267

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern