Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CFI
  • Mouse genes Cfi
  • Rat genes Cfi
  • Zfish genes cfi
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cfi

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CFI	IPI	UniProtKB:P0C045	Human	PMID:16237761
Cellular Component	GO:0070062	extracellular exosome	CFI	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CFI	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CFI	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Cfi	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Cfi	IDA		Rat	PMID:11530941|RGD:8662322
Cellular Component	GO:0005634	nucleus	Cfi	IDA		Rat	PMID:23727008|RGD:8662317
Biological Process	GO:0071354	cellular response to interleukin-6	Cfi	IEP		Rat	PMID:11530941|RGD:8662322
Biological Process	GO:0006956	complement activation	Cfi	IMP		Mouse	PMID:18202746
Biological Process	GO:0061304	retinal blood vessel morphogenesis	cfi	IMP	ZFIN:ZDB-MRPHLNO-130814-3	Zfish	PMID:23685748

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern