Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cftr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CFTR
- Mouse genes Cftr
- Rat genes Cftr
- Zfish genes cftr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cftr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	cftr	IDA		Zfish	PMID:28735752
Molecular Function	GO:0016887	ATP hydrolysis activity	CFTR	IDA		Human	PMID:11524016
Molecular Function	GO:0016887	ATP hydrolysis activity	CFTR	IDA		Human	PMID:8910473
Molecular Function	GO:0016887	ATP hydrolysis activity	cftr	IDA		Zfish	PMID:27912062
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	CFTR	IDA		Human	PMID:15010471
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	CFTR	IDA		Human	PMID:19019741
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	Cftr	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:11524016
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:11707463
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:15010471
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:18570918
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:19019741
Molecular Function	GO:0005254	chloride channel activity	CFTR	IMP		Human	PMID:19621064
Molecular Function	GO:0005254	chloride channel activity	CFTR	IDA		Human	PMID:22178883
Molecular Function	GO:0005254	chloride channel activity	CFTR	IMP		Human	PMID:24885604
Molecular Function	GO:0005254	chloride channel activity	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Molecular Function	GO:0005254	chloride channel activity	Cftr	IDA		Mouse	MGI:MGI:4439399\|PMID:20231442
Molecular Function	GO:0005254	chloride channel activity	cftr	IDA		Zfish	PMID:32123813
Molecular Function	GO:0019869	chloride channel inhibitor activity	CFTR	IDA		Human	PMID:22178883
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Cftr	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0019899	enzyme binding	CFTR	IPI	UniProtKB:Q14694	Human	PMID:19398555
Molecular Function	GO:0005260	intracellularly ATP-gated chloride channel activity	CFTR	IMP		Human	PMID:8910473
Molecular Function	GO:0030165	PDZ domain binding	CFTR	IDA		Human	PMID:11707463
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9HD26	Human	PMID:11707463
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q15599	Human	PMID:12369822
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P51790-2	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q5T2W1	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9HD26	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P98082	Human	PMID:15247260
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9UM54-1	Human	PMID:15247260
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q15599	Human	PMID:16203867
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9HBW0	Human	PMID:16203867
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P27824	Human	PMID:16546175
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q99942	Human	PMID:16901789
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9BUN8	Human	PMID:16901789
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:17110338
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P27824	Human	PMID:17110338
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q15599	Human	PMID:17110338
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:17244609
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9QX74	Human	PMID:17244609
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P51572	Human	PMID:18555783
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q7LBE3	Human	PMID:19289574
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P19120	Human	PMID:19878303
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q7LBE3	Human	PMID:20658517
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9H8Y8	Human	PMID:21884936
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P05787	Human	PMID:22038833
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P60709	Human	PMID:22038833
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q96RN1	Human	PMID:22121115
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q5XXA6	Human	PMID:22178883
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O43852-1	Human	PMID:22768251
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9P0N8	Human	PMID:23818989
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P16615-1	Human	PMID:25661196
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P60709	Human	PMID:25712891
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O15554	Human	PMID:27092946
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:28360110
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q15599	Human	PMID:28360110
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9HD26	Human	PMID:28360110
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P27824	Human	PMID:29924966
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P60709	Human	PMID:29924966
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P07384	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P27824	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q15599	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:Q9HD26	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:O14745	Human	PMID:9671706
Molecular Function	GO:0005515	protein binding	CFTR	IPI	UniProtKB:P60468	Human	PMID:9792704
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:Q80SW1	Mouse	MGI:MGI:5634882\|PMID:23542070
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:P70441\|UniProtKB:Q8CIW6\|UniProtKB:Q9WVC8	Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:Q80SW1	Mouse	MGI:MGI:3831619\|PMID:19033647
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:Q8CIW6	Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:P19120	Mouse	MGI:MGI:5508577\|PMID:19878303
Molecular Function	GO:0005515	protein binding	Cftr	IPI	UniProtKB:P70441\|UniProtKB:Q9WVC8	Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0005515	protein binding	Cftr	IPI	RGD:68433	Rat	PMID:25270793\|RGD:11567217
Molecular Function	GO:0051087	protein-folding chaperone binding	CFTR	IPI	UniProtKB:O95816	Human	PMID:16207813
Molecular Function	GO:0106138	Sec61 translocon complex binding	CFTR	IDA		Human	PMID:9792704
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:12801959
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:15247260
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:18570918
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IMP		Human	PMID:19621064
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:20658517
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:28130590
Cellular Component	GO:0016324	apical plasma membrane	CFTR	IDA		Human	PMID:32487539
Cellular Component	GO:0016324	apical plasma membrane	Cftr	IDA		Mouse	MGI:MGI:5289719\|PMID:21884936
Cellular Component	GO:0016324	apical plasma membrane	Cftr	IDA		Mouse	PMID:16537650
Cellular Component	GO:0016324	apical plasma membrane	Cftr	IDA		Rat	PMID:11083465\|RGD:724710
Cellular Component	GO:0016324	apical plasma membrane	Cftr	IDA		Rat	PMID:24598307\|RGD:35673329
Cellular Component	GO:0016324	apical plasma membrane	cftr	IDA		Zfish	PMID:25592226
Cellular Component	GO:0016323	basolateral plasma membrane	Cftr	IDA		Rat	PMID:16575514\|RGD:1600701
Cellular Component	GO:0009986	cell surface	CFTR	IDA		Human	PMID:20658517
Cellular Component	GO:0005737	cytoplasm	CFTR	IDA		Human	PMID:18570918
Cellular Component	GO:0005737	cytoplasm	Cftr	IDA		Rat	PMID:16575514\|RGD:1600701
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Cftr	IDA		Rat	PMID:11083465\|RGD:724710
Cellular Component	GO:0005829	cytosol	CFTR	IDA		Human	PMID:24885604
Cellular Component	GO:0005829	cytosol	Cftr	IDA		Mouse	MGI:MGI:5640937\|PMID:24885604
Cellular Component	GO:0030425	dendrite	Cftr	IDA		Rat	PMID:7529593\|RGD:11566043
Cellular Component	GO:0005769	early endosome	CFTR	IDA		Human	PMID:19398555
Cellular Component	GO:0005769	early endosome	Cftr	IDA		Rat	PMID:7521124\|RGD:11567228
Cellular Component	GO:0005789	endoplasmic reticulum membrane	CFTR	IDA		Human	PMID:11707463
Cellular Component	GO:0016020	membrane	CFTR	IDA		Human	PMID:8910473
Cellular Component	GO:0005902	microvillus	Cftr	IDA		Rat	PMID:16575514\|RGD:1600701
Cellular Component	GO:0043025	neuronal cell body	Cftr	IDA		Rat	PMID:7529593\|RGD:11566043
Cellular Component	GO:0005634	nucleus	Cftr	IDA		Rat	PMID:29453757\|RGD:13514091
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:11524016
Cellular Component	GO:0005886	plasma membrane	CFTR	IMP		Human	PMID:11707463
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:15010471
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:21884936
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:22178883
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:24885604
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:28067262
Cellular Component	GO:0005886	plasma membrane	CFTR	IDA		Human	PMID:28130590
Cellular Component	GO:0005886	plasma membrane	Cftr	IDA		Mouse	MGI:MGI:5640937\|PMID:24885604
Cellular Component	GO:0032991	protein-containing complex	CFTR	IDA		Human	PMID:17462998
Cellular Component	GO:0055037	recycling endosome	CFTR	IDA		Human	PMID:18570918
Biological Process	GO:0007568	aging	Cftr	IEP		Rat	PMID:25546515\|RGD:11566048
Biological Process	GO:0097186	amelogenesis	Cftr	IDA		Mouse	MGI:MGI:6716964\|PMID:26403673
Biological Process	GO:0015701	bicarbonate transport	CFTR	IDA		Human	PMID:15010471
Biological Process	GO:0015701	bicarbonate transport	CFTR	IDA		Human	PMID:19019741
Biological Process	GO:0015701	bicarbonate transport	Cftr	IMP		Rat	PMID:19657734\|RGD:2314618
Biological Process	GO:0071454	cellular response to anoxia	Cftr	IEP		Rat	PMID:14975182\|RGD:1599599
Biological Process	GO:0071320	cellular response to cAMP	Cftr	IDA		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:1904322	cellular response to forskolin	CFTR	IDA		Human	PMID:15010471
Biological Process	GO:1904322	cellular response to forskolin	CFTR	IDA		Human	PMID:19621064
Biological Process	GO:0034605	cellular response to heat	Cftr	IEP		Rat	PMID:22777528\|RGD:11567213
Biological Process	GO:0032870	cellular response to hormone stimulus	Cftr	IEP		Rat	PMID:17595518\|RGD:2314620
Biological Process	GO:1902476	chloride transmembrane transport	CFTR	IDA		Human	PMID:11524016
Biological Process	GO:1902476	chloride transmembrane transport	CFTR	IDA		Human	PMID:11707463
Biological Process	GO:1902476	chloride transmembrane transport	CFTR	IDA		Human	PMID:19019741
Biological Process	GO:1902476	chloride transmembrane transport	CFTR	IMP		Human	PMID:19621064
Biological Process	GO:1902476	chloride transmembrane transport	CFTR	IMP		Human	PMID:24885604
Biological Process	GO:1902476	chloride transmembrane transport	Cftr	IDA		Mouse	MGI:MGI:4439399\|PMID:20231442
Biological Process	GO:1902476	chloride transmembrane transport	Cftr	IDA		Mouse	MGI:MGI:6716964\|PMID:26403673
Biological Process	GO:1902476	chloride transmembrane transport	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0006821	chloride transport	Cftr	IGI	MGI:MGI:2385184	Mouse	PMID:19033647
Biological Process	GO:0006821	chloride transport	Cftr	IMP		Rat	PMID:19684200\|RGD:2314617
Biological Process	GO:0006695	cholesterol biosynthetic process	Cftr	IMP	MGI:MGI:1856709	Mouse	PMID:17085523
Biological Process	GO:0030301	cholesterol transport	Cftr	IMP	MGI:MGI:1856709	Mouse	PMID:17085523
Biological Process	GO:0042742	defense response to bacterium	cftr	IMP	ZFIN:ZDB-MRPHLNO-190805-1	Zfish	PMID:30759393
Biological Process	GO:0042742	defense response to bacterium	cftr	IMP	ZFIN:ZDB-MRPHLNO-101104-1,ZFIN:ZDB-MRPHLNO-101104-2	Zfish	PMID:20732993
Biological Process	GO:0035162	embryonic hemopoiesis	cftr	IMP	ZFIN:ZDB-GENO-190715-7	Zfish	PMID:29449653
Biological Process	GO:0035162	embryonic hemopoiesis	cftr	IMP	ZFIN:ZDB-MRPHLNO-101104-2	Zfish	PMID:29449653
Biological Process	GO:0070166	enamel mineralization	Cftr	IMP		Rat	PMID:31942562\|RGD:126928119
Biological Process	GO:0051649	establishment of localization in cell	Cftr	IGI	MGI:MGI:2385184	Mouse	PMID:19033647
Biological Process	GO:0008354	germ cell migration	cftr	IMP	ZFIN:ZDB-GENO-190322-3	Zfish	PMID:29930176
Biological Process	GO:0007507	heart development	cftr	IMP	ZFIN:ZDB-GENO-211104-4	Zfish	PMID:32574800
Biological Process	GO:0045087	innate immune response	cftr	IMP	ZFIN:ZDB-MRPHLNO-190805-1	Zfish	PMID:32849617
Biological Process	GO:0045087	innate immune response	cftr	IMP	ZFIN:ZDB-GENO-220126-1	Zfish	PMID:32849617
Biological Process	GO:0051454	intracellular pH elevation	Cftr	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:0070121	Kupffer's vesicle development	cftr	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-070620-5,ZFIN:ZDB-MRPHLNO-160201-1	Zfish	PMID:26432887
Biological Process	GO:0070121	Kupffer's vesicle development	cftr	IMP	ZFIN:ZDB-MRPHLNO-160201-1	Zfish	PMID:26432887
Biological Process	GO:0070121	Kupffer's vesicle development	cftr	IMP	ZFIN:ZDB-GENO-131101-2	Zfish	PMID:23487313
Biological Process	GO:0097421	liver regeneration	Cftr	IEP		Rat	PMID:1378998\|RGD:11567227
Biological Process	GO:0030324	lung development	Cftr	IMP		Rat	PMID:15694001\|RGD:1599597
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	cftr	IMP	ZFIN:ZDB-GENO-221227-3	Zfish	PMID:33951474
Biological Process	GO:0060081	membrane hyperpolarization	Cftr	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	CFTR	IMP		Human	PMID:19621064
Biological Process	GO:2000077	negative regulation of type B pancreatic cell development	Cftr	IMP		Rat	PMID:23178930\|RGD:11567224
Biological Process	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	Cftr	IMP		Rat	PMID:24999019\|RGD:11567225
Biological Process	GO:0031016	pancreas development	cftr	IMP	ZFIN:ZDB-GENO-131101-2	Zfish	PMID:26153247
Biological Process	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity	CFTR	IMP		Human	PMID:24885604
Biological Process	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0070175	positive regulation of enamel mineralization	Cftr	IDA		Mouse	MGI:MGI:6716964\|PMID:26403673
Biological Process	GO:1904446	positive regulation of establishment of Sertoli cell barrier	Cftr	IMP		Rat	PMID:22777528\|RGD:11567213
Biological Process	GO:0045921	positive regulation of exocytosis	CFTR	IMP		Human	PMID:24885604
Biological Process	GO:0045921	positive regulation of exocytosis	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	CFTR	IGI	UniProtKB:Q5XXA6	Human	PMID:24885604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	CFTR	IMP		Human	PMID:24885604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0033005	positive regulation of mast cell activation	Cftr	IMP		Rat	PMID:11781380\|RGD:11567226
Biological Process	GO:1902943	positive regulation of voltage-gated chloride channel activity	CFTR	IDA		Human	PMID:22006324
Biological Process	GO:0090022	regulation of neutrophil chemotaxis	cftr	IMP	ZFIN:ZDB-MRPHLNO-101104-1,ZFIN:ZDB-MRPHLNO-101104-2	Zfish	PMID:20732993
Biological Process	GO:0002679	respiratory burst involved in defense response	cftr	IMP	ZFIN:ZDB-MRPHLNO-101104-1,ZFIN:ZDB-MRPHLNO-101104-2	Zfish	PMID:20732993
Biological Process	GO:0034097	response to cytokine	Cftr	IEP		Rat	PMID:16051699\|RGD:2314622
Biological Process	GO:0034976	response to endoplasmic reticulum stress	CFTR	IDA		Human	PMID:21884936
Biological Process	GO:0034976	response to endoplasmic reticulum stress	CFTR	IDA		Human	PMID:28067262
Biological Process	GO:0043627	response to estrogen	Cftr	IEP		Rat	PMID:16051669\|RGD:1599595
Biological Process	GO:0043434	response to peptide hormone	Cftr	IEP		Rat	PMID:16614390\|RGD:1599594
Biological Process	GO:0009410	response to xenobiotic stimulus	Cftr	IEP		Rat	PMID:16916328\|RGD:1599592
Biological Process	GO:0009410	response to xenobiotic stimulus	Cftr	IMP		Rat	PMID:31942562\|RGD:126928119
Biological Process	GO:0035725	sodium ion transmembrane transport	Cftr	IMP		Rat	PMID:31942562\|RGD:126928119
Biological Process	GO:0060063	Spemann organizer formation at the embryonic shield	cftr	IMP	ZFIN:ZDB-GENO-230303-1	Zfish	PMID:33063835
Biological Process	GO:0048240	sperm capacitation	Cftr	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:0030217	T cell differentiation	cftr	IMP	ZFIN:ZDB-GENO-221227-3	Zfish	PMID:33951474
Biological Process	GO:0030321	transepithelial chloride transport	Cftr	IMP		Rat	PMID:17122162\|RGD:1599591
Biological Process	GO:0030321	transepithelial chloride transport	Cftr	IMP		Rat	PMID:31942562\|RGD:126928119
Biological Process	GO:0035377	transepithelial water transport	CFTR	IMP		Human	PMID:19621064
Biological Process	GO:0042311	vasodilation	Cftr	IMP		Rat	PMID:16859673\|RGD:1599593
Biological Process	GO:0042311	vasodilation	Cftr	IDA		Rat	PMID:17596272\|RGD:2314621
Biological Process	GO:0006904	vesicle docking involved in exocytosis	Cftr	IMP		Mouse	MGI:MGI:5640937\|PMID:24885604
Biological Process	GO:0006833	water transport	Cftr	IMP		Rat	PMID:19657734\|RGD:2314618

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.