Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cgas

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CGAS
- Mouse genes Cgas
- Rat genes Cgas
- Zfish genes cgasa
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cgas

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	EXP		Human	PMID:23258412
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:23258413
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:24077100
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:26300263
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:28214358
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:28363908
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:28738408
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:28934246
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:29426904
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:29937271
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:30007416
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:32792394
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	CGAS	IDA		Human	PMID:33542149
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:6270846\|PMID:30007416
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:5909141\|PMID:28759889
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:6119245\|PMID:29426904
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:5897502\|PMID:28214358
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:5770179\|PMID:26829768
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:5926304\|PMID:28963528
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Molecular Function	GO:0061501	2',3'-cyclic GMP-AMP synthase activity	cgasa	IDA		Zfish	PMID:31877895
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:28738408
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:32817552
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:33051594
Molecular Function	GO:0003682	chromatin binding	CGAS	IDA		Human	PMID:33542149
Molecular Function	GO:0003682	chromatin binding	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Molecular Function	GO:0003682	chromatin binding	Cgas	IDA		Mouse	MGI:MGI:5909141\|PMID:28759889
Molecular Function	GO:0003682	chromatin binding	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Molecular Function	GO:0003682	chromatin binding	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Molecular Function	GO:0003682	chromatin binding	Cgas	IDA		Mouse	MGI:MGI:5909142\|PMID:28759028
Molecular Function	GO:0003677	DNA binding	CGAS	IDA		Human	PMID:23258413
Molecular Function	GO:0003677	DNA binding	Cgas	IDA		Mouse	MGI:MGI:5770179\|PMID:26829768
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:24077100
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:28363908
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:29937271
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:30007416
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:32792394
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:32817552
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:33051594
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:33542149
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:35438208
Molecular Function	GO:0003690	double-stranded DNA binding	CGAS	IDA		Human	PMID:35460603
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:5897489\|PMID:28363908
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:6270846\|PMID:30007416
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:5897502\|PMID:28214358
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Molecular Function	GO:0003690	double-stranded DNA binding	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Molecular Function	GO:0008047	enzyme activator activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0008047	enzyme activator activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0140693	molecular condensate scaffold activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0140693	molecular condensate scaffold activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0140693	molecular condensate scaffold activity	CGAS	IDA		Human	PMID:35322803
Molecular Function	GO:0140677	molecular function activator activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0140677	molecular function activator activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0140678	molecular function inhibitor activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0140678	molecular function inhibitor activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0031491	nucleosome binding	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0031491	nucleosome binding	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0031491	nucleosome binding	CGAS	IDA		Human	PMID:33051594
Molecular Function	GO:0031491	nucleosome binding	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Molecular Function	GO:0031491	nucleosome binding	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Molecular Function	GO:0031491	nucleosome binding	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	CGAS	IDA		Human	PMID:30827685
Molecular Function	GO:0160004	poly-ADP-D-ribose modification-dependent protein binding	Cgas	IDA		Mouse	PMID:35210392
Molecular Function	GO:0005515	protein binding	CGAS	IPI	UniProtKB:O60828	Human	PMID:26046437
Molecular Function	GO:0005515	protein binding	CGAS	IPI	UniProtKB:Q9NUD5	Human	PMID:30135424
Molecular Function	GO:0005515	protein binding	CGAS	IPI	UniProtKB:Q13283	Human	PMID:30510222
Molecular Function	GO:0005515	protein binding	CGAS	IPI	UniProtKB:Q15366	Human	PMID:35322803
Molecular Function	GO:0005515	protein binding	Cgas	IPI	UniProtKB:A4Q9E8\|UniProtKB:Q80UG8	Mouse	MGI:MGI:5770179\|PMID:26829768
Molecular Function	GO:0005515	protein binding	Cgas	IPI	UniProtKB:P09874	Mouse	MGI:MGI:6241455\|PMID:30356214
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:29426904
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:32911482
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:32912999
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:33051594
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:33542149
Molecular Function	GO:0042803	protein homodimerization activity	CGAS	IDA		Human	PMID:35438208
Molecular Function	GO:0042803	protein homodimerization activity	Cgas	IDA		Mouse	MGI:MGI:6119245\|PMID:29426904
Molecular Function	GO:0042803	protein homodimerization activity	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Molecular Function	GO:0042803	protein homodimerization activity	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Molecular Function	GO:0042803	protein homodimerization activity	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Cellular Component	GO:0005737	cytoplasm	CGAS	IDA		Human	PMID:23258413
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:32912999
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:35438208
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:23258413
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:29937271
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:30356214
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:30827685
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:31544964
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:32792394
Cellular Component	GO:0005829	cytosol	CGAS	IDA		Human	PMID:33406424
Cellular Component	GO:0005829	cytosol	Cgas	IDA		Mouse	MGI:MGI:6294227\|PMID:30827685
Cellular Component	GO:0005829	cytosol	Cgas	IDA		Mouse	MGI:MGI:5487472\|PMID:23258413
Cellular Component	GO:0005829	cytosol	Cgas	IDA		Mouse	MGI:MGI:6370284\|PMID:31544964
Cellular Component	GO:0016604	nuclear body	CGAS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CGAS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:29937271
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:30356214
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:31544964
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:32792394
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:33230297
Cellular Component	GO:0005634	nucleus	CGAS	IDA		Human	PMID:33406424
Cellular Component	GO:0005634	nucleus	Cgas	IDA		Mouse	MGI:MGI:6370284\|PMID:31544964
Cellular Component	GO:0005634	nucleus	Cgas	IDA		Mouse	PMID:35210392
Cellular Component	GO:0005886	plasma membrane	CGAS	IDA		Human	PMID:30827685
Cellular Component	GO:0005886	plasma membrane	Cgas	IDA		Mouse	MGI:MGI:6294227\|PMID:30827685
Cellular Component	GO:0035861	site of double-strand break	CGAS	IDA		Human	PMID:30356214
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:0002218	activation of innate immune response	CGAS	IMP		Human	PMID:23258413
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:23929945
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:26046437
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:28363908
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:29426904
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:30007416
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:32817552
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:32911482
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:32912999
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:33542149
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:35322803
Biological Process	GO:0002218	activation of innate immune response	CGAS	IDA		Human	PMID:35438208
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:5505711\|PMID:23929945
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:6119245\|PMID:29426904
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:6828894\|PMID:32913000
Biological Process	GO:0002218	activation of innate immune response	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:6810288\|PMID:32911481
Biological Process	GO:0002218	activation of innate immune response	Cgas	IDA		Mouse	MGI:MGI:6754862\|PMID:32911480
Biological Process	GO:0019933	cAMP-mediated signaling	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:0019933	cAMP-mediated signaling	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0019933	cAMP-mediated signaling	CGAS	IDA		Human	PMID:28738408
Biological Process	GO:0019933	cAMP-mediated signaling	CGAS	IDA		Human	PMID:30007416
Biological Process	GO:0019933	cAMP-mediated signaling	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Biological Process	GO:0019933	cAMP-mediated signaling	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0019933	cAMP-mediated signaling	Cgas	IDA		Mouse	MGI:MGI:5909141\|PMID:28759889
Biological Process	GO:0019933	cAMP-mediated signaling	Cgas	IDA		Mouse	MGI:MGI:6270846\|PMID:30007416
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Cgas	IDA		Mouse	MGI:MGI:5897502\|PMID:28214358
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Cgas	IDA		Mouse	MGI:MGI:5897489\|PMID:28363908
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0019934	cGMP-mediated signaling	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:0019934	cGMP-mediated signaling	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0019934	cGMP-mediated signaling	CGAS	IDA		Human	PMID:28738408
Biological Process	GO:0019934	cGMP-mediated signaling	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Biological Process	GO:0019934	cGMP-mediated signaling	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0019934	cGMP-mediated signaling	Cgas	IDA		Mouse	MGI:MGI:5909141\|PMID:28759889
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:0051607	defense response to virus	CGAS	IDA		Human	PMID:21478870
Biological Process	GO:0051607	defense response to virus	CGAS	IDA		Human	PMID:23929945
Biological Process	GO:0051607	defense response to virus	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0051607	defense response to virus	CGAS	IDA		Human	PMID:26046437
Biological Process	GO:0051607	defense response to virus	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0051607	defense response to virus	Cgas	IDA		Mouse	MGI:MGI:5505711\|PMID:23929945
Biological Process	GO:0008340	determination of adult lifespan	Cgas	IGI	MGI:MGI:1328317	Mouse	PMID:26371324
Biological Process	GO:0006974	DNA damage response	CGAS	IDA		Human	PMID:28738408
Biological Process	GO:0045087	innate immune response	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:0045087	innate immune response	cgasa	IMP	ZFIN:ZDB-MRPHLNO-210304-1	Zfish	PMID:32285982
Biological Process	GO:0045738	negative regulation of DNA repair	Cgas	IDA		Mouse	PMID:35210392
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	CGAS	IDA		Human	PMID:30356214
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	CGAS	IDA		Human	PMID:31544964
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	Cgas	IDA		Mouse	MGI:MGI:6370284\|PMID:31544964
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	Cgas	IMP		Mouse	MGI:MGI:6241455\|PMID:30356214
Biological Process	GO:0045824	negative regulation of innate immune response	CGAS	IDA		Human	PMID:32911482
Biological Process	GO:0045824	negative regulation of innate immune response	CGAS	IDA		Human	PMID:32912999
Biological Process	GO:0038001	paracrine signaling	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0038001	paracrine signaling	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0038001	paracrine signaling	Cgas	IDA		Mouse	MGI:MGI:5909142\|PMID:28759028
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	CGAS	IDA		Human	PMID:23258413
Biological Process	GO:2000774	positive regulation of cellular senescence	Cgas	IDA		Mouse	MGI:MGI:5909142\|PMID:28759028
Biological Process	GO:0002230	positive regulation of defense response to virus by host	CGAS	IMP		Human	PMID:23258413
Biological Process	GO:0002230	positive regulation of defense response to virus by host	CGAS	IDA		Human	PMID:23929945
Biological Process	GO:0002230	positive regulation of defense response to virus by host	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0002230	positive regulation of defense response to virus by host	CGAS	IDA		Human	PMID:26046437
Biological Process	GO:0002230	positive regulation of defense response to virus by host	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0002230	positive regulation of defense response to virus by host	Cgas	IMP		Mouse	MGI:MGI:5487472\|PMID:23258413
Biological Process	GO:0002230	positive regulation of defense response to virus by host	Cgas	IDA		Mouse	MGI:MGI:5505711\|PMID:23929945
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:24077100
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:26046437
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:28363908
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:28738408
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:32792394
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:33230297
Biological Process	GO:0032481	positive regulation of type I interferon production	CGAS	IDA		Human	PMID:33406424
Biological Process	GO:0032481	positive regulation of type I interferon production	Cgas	IDA		Mouse	MGI:MGI:5909141\|PMID:28759889
Biological Process	GO:0032481	positive regulation of type I interferon production	Cgas	IDA		Mouse	MGI:MGI:5908326\|PMID:24077100
Biological Process	GO:0032481	positive regulation of type I interferon production	Cgas	IDA		Mouse	MGI:MGI:5909142\|PMID:28759028
Biological Process	GO:0006144	purine nucleobase metabolic process	cgasa	IDA		Zfish	PMID:32285982
Biological Process	GO:0050776	regulation of immune response	Cgas	IGI	MGI:MGI:1329019	Mouse	PMID:26371324
Biological Process	GO:0002637	regulation of immunoglobulin production	Cgas	IGI	MGI:MGI:1328317	Mouse	PMID:26371324
Biological Process	GO:0045088	regulation of innate immune response	CGAS	IDA		Human	PMID:32911482
Biological Process	GO:0045088	regulation of innate immune response	CGAS	IDA		Human	PMID:32912999
Biological Process	GO:0045088	regulation of innate immune response	CGAS	IDA		Human	PMID:35438208
Biological Process	GO:0045088	regulation of innate immune response	CGAS	IDA		Human	PMID:35460603
Biological Process	GO:0050863	regulation of T cell activation	Cgas	IGI	MGI:MGI:1328317	Mouse	PMID:26371324
Biological Process	GO:0032479	regulation of type I interferon production	Cgas	IGI	MGI:MGI:1328317	Mouse	PMID:26371324

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.