Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHAT
  • Mouse genes Chat
  • Rat genes Chat
  • Zfish genes chata,chatb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033265	choline binding	Chat	IDA		Rat	PMID:126256|RGD:2301195
Molecular Function	GO:0033265	choline binding	Chat	IDA		Rat	PMID:4008917|RGD:2301203
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IMP	MGI:MGI:3045900	Mouse	PMID:12441053
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:12533614
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IDA		Rat	PMID:126256|RGD:2301195
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IDA		Rat	PMID:334962|RGD:2301197
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IDA		Rat	PMID:4008917|RGD:2301203
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IDA		Rat	PMID:6619842|RGD:1600852
Molecular Function	GO:0004102	choline O-acetyltransferase activity	Chat	IDA		Rat	PMID:6854006|RGD:2301199
Cellular Component	GO:0030424	axon	Chat	IDA		Mouse	PMID:20176735
Cellular Component	GO:0030424	axon	Chat	IDA		Mouse	PMID:19906978
Cellular Component	GO:0005737	cytoplasm	Chat	IDA		Mouse	PMID:24462097
Cellular Component	GO:0005739	mitochondrion	Chat	HDA		Mouse	PMID:18614015
Cellular Component	GO:0043005	neuron projection	Chat	IDA		Mouse	PMID:12115678
Cellular Component	GO:0043005	neuron projection	Chat	IDA		Rat	PMID:6619842|RGD:1600852
Cellular Component	GO:0043025	neuronal cell body	Chat	IDA		Mouse	PMID:9853118
Biological Process	GO:0008292	acetylcholine biosynthetic process	Chat	IDA		Rat	PMID:126256|RGD:2301195
Biological Process	GO:0008292	acetylcholine biosynthetic process	Chat	IDA		Rat	PMID:334962|RGD:2301197
Biological Process	GO:0008292	acetylcholine biosynthetic process	Chat	IDA		Rat	PMID:4008917|RGD:2301203
Biological Process	GO:0008292	acetylcholine biosynthetic process	Chat	IDA		Rat	PMID:6854006|RGD:2301199
Biological Process	GO:0007628	adult walking behavior	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:15820692
Biological Process	GO:0001547	antral ovarian follicle growth	Chat	IEP		Rat	PMID:16846505|RGD:1600848
Biological Process	GO:0007268	chemical synaptic transmission	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:12533614
Biological Process	GO:0016358	dendrite development	Chat	IMP	MGI:MGI:3045900	Mouse	PMID:12441053
Biological Process	GO:0007529	establishment of synaptic specificity at neuromuscular junction	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:12533614
Biological Process	GO:0007626	locomotory behavior	chata	IMP		Zfish	PMID:18684905|ZFIN:ZDB-PUB-080825-29
Biological Process	GO:0007613	memory	Chat	IMP		Rat	PMID:16854393|RGD:1600846
Biological Process	GO:0007517	muscle organ development	Chat	IMP	MGI:MGI:3045900	Mouse	PMID:12441053
Biological Process	GO:0007274	neuromuscular synaptic transmission	Chat	IMP	MGI:MGI:3045900	Mouse	PMID:12441053
Biological Process	GO:0030182	neuron differentiation	Chat	IMP	MGI:MGI:3045900	Mouse	PMID:12441053
Biological Process	GO:0045471	response to ethanol	Chat	IEP		Rat	PMID:17045751|RGD:1600844
Biological Process	GO:0001666	response to hypoxia	Chat	IEP		Rat	PMID:17218023|RGD:1600836
Biological Process	GO:0007584	response to nutrient	Chat	IEP		Rat	PMID:17192613|RGD:1600843
Biological Process	GO:0009410	response to xenobiotic stimulus	Chat	IEP		Rat	PMID:17374747|RGD:1600833
Biological Process	GO:0007622	rhythmic behavior	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:15820692
Biological Process	GO:0043179	rhythmic excitation	Chat	IMP	MGI:MGI:2450310	Mouse	PMID:15820692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern