Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHD5
  • Mouse genes Chd5
  • Rat genes Chd5
  • Zfish genes chd5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chd5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Chd5	IDA		Rat	PMID:21931736|RGD:8553453
Molecular Function	GO:0061628	H3K27me3 modified histone binding	CHD5	IDA		Human	PMID:23948251
Molecular Function	GO:0061628	H3K27me3 modified histone binding	Chd5	IDA		Mouse	MGI:MGI:5532595|PMID:23948251
Molecular Function	GO:0042393	histone binding	Chd5	IDA		Mouse	MGI:MGI:5559659|PMID:23318260
Molecular Function	GO:0042826	histone deacetylase binding	Chd5	IPI	UniProtKB:O09106|UniProtKB:P70288	Mouse	MGI:MGI:5559665|PMID:21931736
Molecular Function	GO:0005515	protein binding	CHD5	IPI	UniProtKB:O75381	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Chd5	IPI	UniProtKB:Q8VHR5|UniProtKB:Q924K8	Mouse	MGI:MGI:5559665|PMID:21931736
Cellular Component	GO:0000785	chromatin	Chd5	IDA		Rat	PMID:21931736|RGD:8553453
Cellular Component	GO:0005829	cytosol	CHD5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000792	heterochromatin	Chd5	IDA		Mouse	MGI:MGI:5559659|PMID:23318260
Cellular Component	GO:0016020	membrane	CHD5	HDA		Human	PMID:19946888
Cellular Component	GO:0016607	nuclear speck	CHD5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CHD5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CHD5	IDA		Human	PMID:21931736
Cellular Component	GO:0005634	nucleus	Chd5	IDA		Mouse	MGI:MGI:5532595|PMID:23948251
Cellular Component	GO:0005634	nucleus	Chd5	IDA		Rat	PMID:12189208|RGD:729665
Cellular Component	GO:0005634	nucleus	Chd5	IDA		Rat	PMID:21931736|RGD:8553453
Cellular Component	GO:0016581	NuRD complex	Chd5	IDA		Mouse	MGI:MGI:5559665|PMID:21931736
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Chd5	IMP		Mouse	MGI:MGI:5532595|PMID:23948251
Biological Process	GO:0006338	chromatin remodeling	chd5	IDA		Zfish	PMID:26092436
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	chd5	IMP	ZFIN:ZDB-MRPHLNO-151208-6	Zfish	PMID:26092436
Biological Process	GO:0060322	head development	chd5	IMP	ZFIN:ZDB-MRPHLNO-151208-6	Zfish	PMID:26092436
Biological Process	GO:0098532	histone H3-K27 trimethylation	CHD5	IMP		Human	PMID:23948251
Biological Process	GO:0008285	negative regulation of cell population proliferation	Chd5	IMP		Mouse	MGI:MGI:5559659|PMID:23318260
Biological Process	GO:0008285	negative regulation of cell population proliferation	Chd5	IMP		Mouse	MGI:MGI:3711389|PMID:17289567
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Chd5	IMP		Mouse	MGI:MGI:5559659|PMID:23318260
Biological Process	GO:1901798	positive regulation of signal transduction by p53 class mediator	Chd5	IMP		Mouse	MGI:MGI:3711389|PMID:17289567
Biological Process	GO:0045595	regulation of cell differentiation	Chd5	IMP		Mouse	MGI:MGI:5559659|PMID:23318260
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	CHD5	IMP		Human	PMID:23948251
Biological Process	GO:0035092	sperm DNA condensation	Chd5	IMP		Mouse	MGI:MGI:5559810|PMID:24252660
Biological Process	GO:0006366	transcription by RNA polymerase II	Chd5	IMP		Rat	PMID:21931736|RGD:8553453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern