Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHD7
  • Mouse genes Chd7
  • Rat genes Chd7
  • Zfish genes chd7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chd7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990841	promoter-specific chromatin binding	Chd7	IDA		Mouse	PMID:26102480
Molecular Function	GO:0005515	protein binding	CHD7	IPI	UniProtKB:Q86U86	Human	PMID:20130577
Molecular Function	GO:0005515	protein binding	CHD7	IPI	UniProtKB:Q8TAQ2	Human	PMID:20130577
Molecular Function	GO:0005515	protein binding	CHD7	IPI	UniProtKB:Q9HCK8	Human	PMID:20453063
Molecular Function	GO:0005515	protein binding	CHD7	IPI	UniProtKB:Q9HCK8-2	Human	PMID:20453063
Molecular Function	GO:0005515	protein binding	Chd7	IPI	UniProtKB:Q60I23	Mouse	MGI:MGI:5437412|PMID:21532573
Molecular Function	GO:0005515	protein binding	Chd7	IPI	PR:P70207	Mouse	PMID:23319608
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Chd7	IDA		Mouse	PMID:23319608
Cellular Component	GO:0005730	nucleolus	CHD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CHD7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CHD7	IDA		Human	PMID:20453063
Cellular Component	GO:0005634	nucleus	Chd7	IDA		Mouse	PMID:26102480
Biological Process	GO:0007512	adult heart development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0007628	adult walking behavior	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0035904	aorta development	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0035909	aorta morphogenesis	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0048844	artery morphogenesis	Chd7	IGI	MGI:MGI:98493	Mouse	PMID:19855134
Biological Process	GO:0036302	atrioventricular canal development	Chd7	IMP	MGI:MGI:2450311,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0008015	blood circulation	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0001568	blood vessel development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0001974	blood vessel remodeling	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0030282	bone mineralization	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0043010	camera-type eye development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0060411	cardiac septum morphogenesis	Chd7	IMP	MGI:MGI:2450311,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0051216	cartilage development	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:23920116
Biological Process	GO:0007417	central nervous system development	CHD7	IMP		Human	PMID:9556299
Biological Process	GO:0043009	chordate embryonic development	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:23920116
Biological Process	GO:0006338	chromatin remodeling	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0050890	cognition	CHD7	IMP		Human	PMID:16155193
Biological Process	GO:0021545	cranial nerve development	CHD7	IMP		Human	PMID:9556299
Biological Process	GO:0021602	cranial nerve morphogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:1904888	cranial skeletal system development	chd7	IGI	ZFIN:ZDB-MRPHLNO-170208-2,ZFIN:ZDB-MRPHLNO-170208-3	Zfish	PMID:27418670
Biological Process	GO:1904888	cranial skeletal system development	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:27418670
Biological Process	GO:1904888	cranial skeletal system development	chd7	IGI	ZFIN:ZDB-MRPHLNO-051220-4,ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:1904888	cranial skeletal system development	chd7	IMP	ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0007368	determination of left/right symmetry	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:21901784
Biological Process	GO:0048546	digestive tract morphogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-3	Zfish	PMID:29660852
Biological Process	GO:0042471	ear morphogenesis	Chd7	IMP	MGI:MGI:1862038	Mouse	PMID:10932191
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	chd7	IGI	ZFIN:ZDB-MRPHLNO-131211-1,ZFIN:ZDB-MRPHLNO-131211-4	Zfish	PMID:23920116
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:23920116
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0060429	epithelium development	Chd7	IMP	MGI:MGI:3707678	Mouse	PMID:19279158
Biological Process	GO:0060324	face development	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0030540	female genitalia development	Chd7	IMP	MGI:MGI:3511552	Mouse	PMID:16207732
Biological Process	GO:0030540	female genitalia development	Chd7	IMP	MGI:MGI:3588652	Mouse	PMID:16207732
Biological Process	GO:0030540	female genitalia development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0048806	genitalia development	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0007507	heart development	chd7	IMP	ZFIN:ZDB-GENO-171117-12	Zfish	PMID:28280001
Biological Process	GO:0001947	heart looping	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0003007	heart morphogenesis	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0003007	heart morphogenesis	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	chd7	IMP		Zfish	PMID:24240475
Biological Process	GO:0001701	in utero embryonic development	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0001701	in utero embryonic development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0042472	inner ear morphogenesis	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0042472	inner ear morphogenesis	Chd7	IMP	MGI:MGI:3511552	Mouse	PMID:15353999
Biological Process	GO:0042472	inner ear morphogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0060384	innervation	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0120054	intestinal motility	chd7	IMP	ZFIN:ZDB-GENO-181009-15	Zfish	PMID:29660852
Biological Process	GO:0120054	intestinal motility	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-3	Zfish	PMID:29660852
Biological Process	GO:0060173	limb development	CHD7	IMP		Human	PMID:17937444
Biological Process	GO:0007626	locomotory behavior	Chd7	IMP	MGI:MGI:1862038	Mouse	PMID:10932191
Biological Process	GO:0042552	myelination	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1,ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:31051269
Biological Process	GO:0022011	myelination in peripheral nervous system	chd7	IMP	ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0022011	myelination in peripheral nervous system	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:27418670
Biological Process	GO:0022011	myelination in peripheral nervous system	chd7	IGI	ZFIN:ZDB-MRPHLNO-051220-4,ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0022011	myelination in peripheral nervous system	chd7	IGI	ZFIN:ZDB-MRPHLNO-170208-2,ZFIN:ZDB-MRPHLNO-170208-3	Zfish	PMID:27418670
Biological Process	GO:0001755	neural crest cell migration	chd7	IMP	ZFIN:ZDB-GENO-181031-7	Zfish	PMID:31464029
Biological Process	GO:0001755	neural crest cell migration	chd7	IMP	ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0001755	neural crest cell migration	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:27418670
Biological Process	GO:0014029	neural crest formation	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0048666	neuron development	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1,ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:31051269
Biological Process	GO:0048812	neuron projection morphogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-3	Zfish	PMID:29660852
Biological Process	GO:0048812	neuron projection morphogenesis	chd7	IMP	ZFIN:ZDB-GENO-181009-15	Zfish	PMID:29660852
Biological Process	GO:0043584	nose development	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0043584	nose development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0042048	olfactory behavior	Chd7	IMP	MGI:MGI:3707678	Mouse	PMID:19279158
Biological Process	GO:0021772	olfactory bulb development	Chd7	IMP	MGI:MGI:3707678	Mouse	PMID:19279158
Biological Process	GO:0021553	olfactory nerve development	Chd7	IMP		Mouse	PMID:19279158
Biological Process	GO:0048840	otolith development	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-2	Zfish	PMID:25472840
Biological Process	GO:0048935	peripheral nervous system neuron development	chd7	IMP	ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0048935	peripheral nervous system neuron development	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:27418670
Biological Process	GO:0043473	pigmentation	chd7	IMP	ZFIN:ZDB-MRPHLNO-131211-1	Zfish	PMID:27418670
Biological Process	GO:0043473	pigmentation	chd7	IMP	ZFIN:ZDB-MRPHLNO-170208-2	Zfish	PMID:27418670
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0060319	primitive erythrocyte differentiation	chd7	IMP		Zfish	PMID:24240475
Biological Process	GO:0060123	regulation of growth hormone secretion	CHD7	IMP		Human	PMID:9556299
Biological Process	GO:0050767	regulation of neurogenesis	Chd7	IMP	MGI:MGI:3707678	Mouse	PMID:19279158
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0009617	response to bacterium	Chd7	IEP		Mouse	PMID:23012479
Biological Process	GO:0060041	retina development in camera-type eye	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0060041	retina development in camera-type eye	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0003226	right ventricular compact myocardium morphogenesis	Chd7	IMP	MGI:MGI:2450311,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0060021	roof of mouth development	Chd7	IMP	MGI:MGI:3588650	Mouse	PMID:16207732
Biological Process	GO:0009303	rRNA transcription	chd7	IGI	ZFIN:ZDB-MRPHLNO-131211-1,ZFIN:ZDB-MRPHLNO-131211-4	Zfish	PMID:23920116
Biological Process	GO:0062009	secondary palate development	CHD7	IMP		Human	PMID:15300250
Biological Process	GO:0048752	semicircular canal morphogenesis	Chd7	IGI	MGI:MGI:98493	Mouse	PMID:19855134
Biological Process	GO:0007605	sensory perception of sound	Chd7	IMP	MGI:MGI:1862038	Mouse	PMID:10932191
Biological Process	GO:0001501	skeletal system development	CHD7	IMP		Human	PMID:16155193
Biological Process	GO:0001756	somitogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-2	Zfish	PMID:21901784
Biological Process	GO:0001756	somitogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:22363697
Biological Process	GO:0001756	somitogenesis	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:21901784
Biological Process	GO:0048798	swim bladder inflation	chd7	IMP	ZFIN:ZDB-GENO-171117-12	Zfish	PMID:28280001
Biological Process	GO:0030217	T cell differentiation	CHD7	IMP		Human	PMID:17684005
Biological Process	GO:0030217	T cell differentiation	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-2	Zfish	PMID:29353058
Biological Process	GO:0048538	thymus development	chd7	IMP	ZFIN:ZDB-GENO-181031-7	Zfish	PMID:29353058
Biological Process	GO:0048538	thymus development	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-1	Zfish	PMID:29353058
Biological Process	GO:0048538	thymus development	chd7	IMP	ZFIN:ZDB-MRPHLNO-111012-2	Zfish	PMID:29353058
Biological Process	GO:0048771	tissue remodeling	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0006366	transcription by RNA polymerase II	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	Chd7	IMP	MGI:MGI:2176467,MGI:MGI:4433295	Mouse	PMID:26102480

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern