Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHFR
  • Mouse genes Chfr
  • Rat genes Chfr
  • Zfish genes chfr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Chfr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000166	nucleotide binding	CHFR	IDA		Human	PMID:18172500
Molecular Function	GO:0005515	protein binding	CHFR	IPI	UniProtKB:P29590	Human	PMID:15467728
Molecular Function	GO:0005515	protein binding	CHFR	IPI	UniProtKB:P09874	Human	PMID:18172500
Molecular Function	GO:0005515	protein binding	CHFR	IPI	UniProtKB:Q13547	Human	PMID:19182791
Molecular Function	GO:0005515	protein binding	CHFR	IPI	UniProtKB:Q92769	Human	PMID:19182791
Molecular Function	GO:0005515	protein binding	Chfr	IPI	PR:Q3TKT4	Mouse	PMID:22285184
Molecular Function	GO:0005515	protein binding	Chfr	IPI	PR:Q9Z0H3	Mouse	PMID:22285184
Molecular Function	GO:0005515	protein binding	Chfr	IPI	PR:Q61466	Mouse	PMID:22285184
Molecular Function	GO:0005515	protein binding	Chfr	IPI	PR:P97477	Mouse	PMID:15793587
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Chfr	IMP	MGI:MGI:3576266	Mouse	PMID:15793587
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	CHFR	IDA		Human	PMID:18172500
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	CHFR	IDA		Human	PMID:19182791
Cellular Component	GO:0005634	nucleus	CHFR	IDA		Human	PMID:18172500
Cellular Component	GO:0016605	PML body	CHFR	IDA		Human	PMID:15467728
Biological Process	GO:0044779	meiotic spindle checkpoint signaling	CHFR	IMP		Human	PMID:10935642
Biological Process	GO:0000278	mitotic cell cycle	Chfr	IMP	MGI:MGI:3576266	Mouse	PMID:15793587
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	CHFR	IMP		Human	PMID:18172500
Biological Process	GO:0044818	mitotic G2/M transition checkpoint	CHFR	IMP		Human	PMID:19182791
Biological Process	GO:0019941	modification-dependent protein catabolic process	CHFR	IDA		Human	PMID:19182791
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Chfr	IDA		Mouse	PMID:22285184
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Chfr	IDA		Mouse	PMID:22285184
Biological Process	GO:0031648	protein destabilization	Chfr	IDA		Mouse	PMID:22285184
Biological Process	GO:0000209	protein polyubiquitination	CHFR	IDA		Human	PMID:19182791
Biological Process	GO:0000209	protein polyubiquitination	Chfr	IDA		Mouse	PMID:15793587
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Chfr	IDA		Mouse	PMID:15793587

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern